Continuous Postoperative Pericardial Flush (CPPF); to evaluate the effects of pericardial flush with a crystalloid on blood loss after valvular surgery and correction for congenital heart disease (CHD).
Completed
- Conditions
- Postoperative blood loss, Cardiac tamponade, Transfusion requirements, Surgical reexploration
- Registration Number
- NL-OMON27629
- Lead Sponsor
- Academic Medical Center (AMC), Amsterdam, The Netherlands
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 170
Inclusion Criteria
All adult patients undergoing surgery for CHD and all adult patients undergoing valvular surgery. Valvular surgery includes single and multiple-valve procedures that involve replacement and/or repair of the aortic-, pulmonary-, mitral- and/or tricuspid valve.
Exclusion Criteria
Patients are not eligible for this study if the following criteria apply:
- Inability to understand study information and/or give informed consent;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1: Mediastinal chest tube drainage (MCTD) 12 hours postoperatively.<br /><br>2: The difference in hemoglobin levels between the start of CPPF and 12 hours postoperative (ΔHb).
- Secondary Outcome Measures
Name Time Method Cardiac tamponade, Transfusion requirements, Surgical reexploration, Postoperative atrial fibrillation, sternal wound infection, mediastinitis, Length of ICU stay and hospitalization, Pericardial and/or pleural effusion at discharge, In-hospital mortality, Mortality, Right ventricular function at six months postoperatively