Understanding the Effect of Variances on Precision in Predictive Coding When Walking to Music and Metronomes in Persons With Cerrebellar Lesions
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Perceptual tempo and rhythm judgements
研究概览
简要总结
This study is a case-control study, involving persons with persons with cerebellar lesions and healthy controls. The study contains 1 descriptive and 3 experimental sessions. In the descriptive session, participant's clinical motor and cognitive functions are collected. In the first experimental session, participant's beat perception and synchronisation abilities is examined within a finger tapping paradigm. In the following experimental sessions participants synchronsiation abilities is examined during walking paradigms, to music and metronomes, with period and phase auditory manipulations. In the latter twp sessions, apart from outcome measures of synchronization the following will be collected as well: brain activity using EEG recordings, spatio-temporal gait parameters, perceived fatigue, perceived motivation and perceived speed of walking.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •diagnosis of cerrebellar lesions
- •walking speed 0.8-1.2m/s, ability to walk for 6 minutes continuously (canes and rollators are permitted)
排除标准
- •cognitive impairment impeding understanding of
- •instructions,
- •beat amusia,
- •deafness,
- •pregnancy
研究组 & 干预措施
persons with cerebellar lesions
干预措施: Synchronisation abilities (Other)
Healthy controls
干预措施: Synchronisation abilities (Other)
结局指标
主要结局
Perceptual tempo and rhythm judgements
时间窗: week 1
subjective indications in regards to what the participants hear in terms
Asynchrony
时间窗: week 1
timing difference between the tap and the beat
6 minute walking test
时间窗: baseline
gait pattern and endurance
cerebellar affective syndrome test
时间窗: baseline
cognitive test
Motricity Index of dorsi flexors, knee extensors and hip flexors
时间窗: baseline
Muscle weakness
Scale for the assessment and rating of ataxia
时间窗: baseline
ataxia
64 channel EEG measurement
时间窗: week 1
neural correlates of entrainment
Time up and Go test
时间窗: baseline
Balance
Dual task questionnaire
时间窗: baseline
troubles a person have when performing a dual task during daily activity
Modified Aschowrth scale Hamstrings, Tricepts Surae, Quadricepts
时间窗: baseline
Spasticity
Dynamic gait index
时间窗: baseline
dynamic balance
Activities-specific balance confidence scale
时间窗: baseline
rating of balance confidence in performing activities of daily life
Modified fatigue impact scale
时间窗: baseline
effect of fatigue
Hospital Anxiety and Depression Scale
时间窗: baseline
determine the levels of anxiety and depression
Relative phase angle
时间窗: week 3
asynchrony in time to quantify synchronization accuracy (in degrees and in milliseconds respectively)
Resultant Vector Length
时间窗: week 3
synchronisation consistency
Resultant Vector Length
时间窗: week 2
synchronisation consistency
Resultant Vector Length
时间窗: week 1
synchronisation consistency
Relative phase angle
时间窗: week 2
asynchrony in time to quantify synchronization accuracy (in degrees and in milliseconds respectively)
次要结局
- Cadencce(week 3)
- Stride length(week 3)
- Double Support(week 3)
- Perceived motivation(week 3)
- Perceived cognitive and physical fatigue(week 3)
- Perceived walking speed(week 3)
- 64 channel EEG measurement (only conducted in 4 PwMS and HC)(week 3)
- Speed(week 3)
- Stride length(week 2)
- Cadencce(week 2)
- Speed(week 2)
- Double Support(week 2)
- Perceived cognitive and physical fatigue(week 2)
- Perceived motivation(week 2)
- Perceived walking speed(week 2)
- 64 channel EEG measurement (only conducted in 4 PwMS and HC)(week 2)
研究者
Peter Feys
Principal Investigator
Hasselt University