The long-term follow-up study on Biomarkers and non-motor symptoms in Parkinson's disease

• Conditions: G20; Parkinson disease

• Registration Number: DRKS00000540
• Lead Sponsor: Paracelsus-Elena-Klinik

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-10-05
• Results First Posted: 2013-08-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 277

Inclusion Criteria

Patients:
-age between 40 and 85 years
-Clinical signs for PD according UK Brain Bank Kriterien
-currently no medication for PD

Controls:
-age between 40 and 85 years

Exclusion Criteria

Patients:
-indication for atypical PD (such as early falls, early and severe autonomic dysfunction, early dementia, supranuclear palsy)
-known severe vascular encephalopathy

Controls:
-Known neurological disorder
-known PD within first degree relatives

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clinical phenotyping and correlation of diagnostic and progression markers for Parkinson's Disease

Secondary Outcome Measures

Name	Time	Method
Establishing a diagnostic algorithm for the early diagnosis of Parkinon's disease