Surgical Outcome of Dorsolumbar Intradural Extramedullary Spinal Cord Tumors

Not Applicable

Recruiting

• Conditions: Spinal Cord Tumor
• Interventions: Procedure: surgical excision

• Registration Number: NCT05678608
• Lead Sponsor: Sohag University

Brief Summary

Primary spinal cord tumors constitute 2-4% of all central nervous system neoplasms; they are classfied as extradural, intradural extramedullary (IDEM: 65%), and intramedullary The most commonly seen IDEM tumors are schwannomas, neurofibromas, and meningiomas. \[1\] The less frequently encountered IDEM tumors include ependymomas, lipomas, hemangiomas, metastatic deposits, paragangliomas, nerve sheath myxomas, and vascular tumors.\[2\] Spinal cord tumors can cause different signs and symptoms, especially as tumors grow. The tumors may affect spinal cord or the nerve roots, blood vessels or bones of spine. Signs and symptoms may include: Pain at the site of the tumor due to tumor growth Back pain, often radiating to other parts of body Feeling less sensitive to pain, heat and cold Loss of bowel or bladder function Difficulty walking, muscle weakness .

MRI is the investigation of choice,however other investigation such CT or X ray are important to ensure stability of the vertebral column and the optimal management is gross total excision for symptomatic lesions.\[3,4\] Over the years, there has been no significant change in the clinical symptoms and pathology of IDEM tumors. However, there have been dramatic improvements in the diagnosis and treatment with the advances of radiological and surgical techniques. Despite advances in operative techniques and neuroimaging, the morbidity associated with the resection of IDEM tumors continues to be significant \[5,6\].

Here, we examined the surgical outcomes of 20 patients with IDEM spinal cord tumors operated in Neurosurgery department at Sohag university Hospital

Detailed Description

Not available

Basic Information
|
Recruitment & Eligibility
|
Study & Design
|
Trial Locations

Study Timeline

• Status Verified: 2022-12
• Study Start: 2022-12-13
• Study First Submitted: 2022-12-19
• Study First Submitted QC: 2022-12-28
• Last Update Submitted: 2022-12-28
• Study First Posted: 2023-01-10
• Last Update Posted: 2023-01-10
• Primary Completion: 2023-05
• Study Completion: 2023-05

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• patients with intradural extramedullary lesion in dorsolumber region

Read More

Exclusion Criteria

• previous history of spinal surgery
• unfit medical patients
• multiple level affection
• associated cervical lesion
• unstable segment

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
spinal cord tumors group	surgical excision	-

Primary Outcome Measures

Name	Time	Method
american spinal injury association scale	6 months	grading of impairment for motor and sensory functions grade A for complete sensory and motor loss grade E for normal motor and sensory
visual analogue pain scale	6 months	pain scale from zero to ten depend on severity of pain,

Trial Locations

Locations (1)

Sohag University Hospital; 🇪🇬 Sohag, Egypt