跳至主要内容
临床试验/NCT02376140
NCT02376140已完成不适用

Food Consumption and Iron Status Survey in Two Provinces of Rural Burkina Faso

Institut de Recherche pour le Developpement0 个研究点目标入组 480 人开始时间: 2010年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
480
主要终点
Usual dietary intakes (quantitative 24-H recalls + repetition on a subsample)

研究概览

简要总结

Sorghum is the primary source of food for more than 300 million people in arid and semi-arid regions of Africa. The grain is one of the few crops that grow well in arid climates, but has a low content in most essential nutrients and is difficult to digest. The African Bio-fortified Sorghum (ABS) Project, a consortium of nine institutions led by Africa Harvest Biotech Foundation International, is working to develop new varieties of sorghum that are easier to digest and contain lower levels of phytates to improve the bioavailability of micronutrients.

In order to determine their target levels, the ABS project needs reliable information on current levels of micronutrient deficiency and consumption patterns of sorghum and nutrients of interest, e.g. iron, zinc, and vitamin A in women and preschool children, which are not currently available in Burkina Faso.

A background nutrition survey among children and women, comprised of two rounds, one in the lean season (July - August) and one in the harvest season (November - January), has been conducted to provide quantitative estimates of sorghum, vitamin A, iron and zinc intakes by women and young children from two rural provinces of Burkina Faso. The survey also had a biochemical component which included blood collection and analysis for indicators of deficiency for vitamin A, iron and zinc. Other important components of this study included anthropometric measurements, household and child morbidity questionnaires, and collection of sorghum samples for analysis of phytate, vitamin A, iron and zinc content.

详细描述

Objectives of the study

The main objectives of the study were:

  • To determine iron, zinc, polyphenolic compounds, and phytate content in raw sorghum grains and cooked sorghum based dishes;
  • To estimate the prevalence and level of sorghum consumption in women and preschool children;
  • To determine the percent contribution of Sorghum to total vitamin A, iron and zinc intake;
  • To assess the prevalence of inadequate intakes of vitamin A, iron and zinc as defined by the cut-point method using Estimated Average Requirements for women and children according to sex and age;
  • To determine the prevalence of micronutrient deficiencies using international (WHO) cut-offs for serum retinol, serum ferritin and serum zinc.

Two secondary methodological objectives were added because of their scientific interest and of their potential practical implications:

  • To assess the performance of dietary diversity scores in reflecting adequacy of micronutrient intakes;
  • To assess the performance of questionnaires on expenditures at the household level in estimating food consumption of household members.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
36 Months 至 59 Months(Child)
性别
All
接受健康志愿者

入选标准

  • to have a child aged 36-59 months with a mother living in the same HH;
  • to give informed consent;
  • not to plan to leave the village before the next round of data collection

排除标准

  • plan to leave the village
  • visible severe unhealthy condition or handicap

结局指标

主要结局

Usual dietary intakes (quantitative 24-H recalls + repetition on a subsample)

时间窗: Up to 2 months data collection repeated 4 months apart (July-August 2010 / November-December 2010)

quantitative 24-H recalls + repetition on a subsample

次要结局

  • Micronutrient status (Biomarkers of vitamin A, iron and zinc + inflammation proteins)(Up to 2 months data collection (November-December 2010))
  • Food composition (Contents of foods in iron, zinc, polyphenolic compounds and phytates)(Up to 2 months data collection repeated 4 months apart (July-August 2010 / November-December 2010))

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Yves MARTIN-PREVEL, MD, PhD

Senior Researcher

Institut de Recherche pour le Developpement

相似试验