IRCT2015090323621N3
Completed
Phase 2
Comparison of induction and ovulation with Clomiphene plus Letrozole versus Clomiphene plus HMG in Clomiphene resistant polycystic ovary syndrome
Vice Chancellor for research of Iran Univercity of Medical Sciences0 sites200 target enrollmentTBD
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Female infertility.
- Sponsor
- Vice Chancellor for research of Iran Univercity of Medical Sciences
- Enrollment
- 200
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Women with history of infertility more over than one year and diagnosis of PCOS based on the revised 2003 consensus on diagnostic criteria; By clomiphene resistance that meant failure of ovulation after 100\-150 mg CC for 5 days for 2\-3 cycles and then resistant to letrozole 2\.5 mg daily for 5 days for 2 cycles. Exclusion criteria: Women older than 40 years or younger than 20; fallopian tubes abnormality proved by hysterosalpingography; abnormal semen analysis for their partners according to the modified criteria of the World Health Organization; endocrine problem like hyper or hypo thyroidism, hyperprolactinemia; abnormal karyotype.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Not specified
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