The EARLY study: Early detection of acute and early-onset cARdiovascuLar toxicitY in children with cancer using a multiparametric approach.
Completed
- Conditions
- cardiomyopathyheart failure10082206
- Registration Number
- NL-OMON49327
- Lead Sponsor
- Prinses Máxima Centrum voor Kinderoncologie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
1) 100 children with cancer receiving anthracyclines according to their
treatment protocol
2) A subgroup of 30 children, aged > 8 years, diagnosed with Hodgkin Lymphoma,
Ewing Sarcoma, Osteosarcoma or Soft Tissue Sarcoma who have MRI evaluation as
part of their tumor response evaluation.
3) a signed informed consent
Exclusion Criteria
Children with
1) severe comorbidity
2) congenital heart disease
3) a history of thoracic radiation or chemotherapy for other malignancies
4) general contraindications for MRI for the patients in the MRI study group.
5) Patients who need anaesthesia for MRI scanning
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method