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A 12-week, Open-Label Extension Study of Lurasidone (SM-13496) in Subjects with Schizophrenia

Phase 3
Completed
Conditions
Schizophrenia
Registration Number
JPRN-jRCT2080223209
Lead Sponsor
Sunovion Pharmaceuticals Inc.,
Brief Summary

The effectiveness data suggest that lurasidone treatment improves positive and negative symptoms of schizophrenia and global symptoms. In addition, there were no unexpected AEs or clinically significant changes in any of the safety parameters. Safety results of this study were consistent with the results from the core study (D1001066) and follow the known safety profile of lurasidone and other atypical antipsychotic drugs of the same class.

Detailed Description

Not available

Recruitment & Eligibility

Status
completed
Sex
All
Target Recruitment
289
Inclusion Criteria

Subject has completed the study D1001066 and has completed all required assessments on the final study visit.
- Subject who are fully informed of and understand the objectives, procedures, and possible benefits and risks of the study and who provide written voluntarily consent to participate in the study etc.

Exclusion Criteria

- Subject is considered by the Investigator to be at imminent risk of suicide or injury to self, or others.
- Subject who are otherwise considered ineligible for the study by the investigator etc.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
safety<br>Adverse events (AEs)<br>Frequency of AE or treatment-related AEs
Secondary Outcome Measures
NameTimeMethod
efficacy<br>PANSS total score<br>Change frome baseline in PANSS total score
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