Quadratus Lumborum Block, analgesic method for postoperative pain therapy after nephrectomy

Phase 1

Conditions: kidney cancer under laparoscopic radical nephrectomy as a curative therapy
MedDRA version: 20.0Level: LLTClassification code 10023400Term: Kidney cancerSystem Organ Class: 100000056053
Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]

Registration Number: EUCTR2017-002254-37-FI

Lead Sponsor: Tampere University Hospital

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Authorised-recruitment may be ongoing or finished

Sex: All

Target Recruitment: 90

Inclusion Criteria

Patients with kidney cancer under laparoscopic nephrectomy as a curative therapy.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 30
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 60

Exclusion Criteria

Age under 18 years, complicated diabetes mellitus type I, lack of finnish language skill and/or co-operation, chronic pain, hepatic insufficiency or other contraindication for paracetamol, steroid medication in regular use, contraindication for oxycodone.

Study & Design

Study Type: Interventional clinical trial of medicinal product

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: Efficacy of Quadratus Lumborum Block for postoperative pain therapy and recovery after laparoscopic radical nephrectomy.;Secondary Objective: Prolonged postoperative pain after laparoscopic radical nephrectomy;Primary end point(s): Cumulative opiate consumption postoperatively;Timepoint(s) of evaluation of this end point: 24 hours after Quadratus Lumborum block placement.

Secondary Outcome Measures

Name	Time	Method
Secondary end point(s): Postoperative analgesic consumption, nausea and vomiting, mobilisation, ileus, other complications, other recovery, length of hospital stay, long term quality of life and prolonged pain;Timepoint(s) of evaluation of this end point: Maximum 72 hours, queries at 2month, 6month, 12month postoperatively