Effect of Eyewash Solution (Commercial washing solution) on the Corneal Epithelium: Adverse Effects of Benzalkonium Chloride on the Eye Surface
Not Applicable
- Conditions
- allergic conjunctivitis
- Registration Number
- JPRN-UMIN000021319
- Lead Sponsor
- Tsurumi University
- Brief Summary
Japan Cornea Conference 2014 and 2015 ARVO 2015 Annual Meeting
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
Subject who the investigator considers ineligible for enrolment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Observation of corneal epithelium disorders (1) Fluorescein vital staining (2) Fluorophotometry 2. Evaluation of corneal epithelial mucin layer (1) Lissamine green vital staining
- Secondary Outcome Measures
Name Time Method Fluorescein staining (2microL) was performed and evaluated initially, by an ophthalmologist before eye washing. Eyes were washed with 20 mL of BSS-plus after 10 minutes to wash away the fluorescein stain solution and, 20 minutes later (30 minutes after fluorescein staining), fluorescein remaining on the cornea was measured using the fluorophotometry. Following this, evaluation by lissamine green staining (2microL) was performed. After eye washing, fluorescein staining evaluation, fluorophotometry measurements, and lissamine green staining evaluation were performed in the same manner as before eye washing, and the results were compared before and after eye washing.