Comparison and evaluation of the effectiveness of oral captopril and oral hydrochlorothiazide in the treatment of urgency hypertensive patients

Islamic Azad University0 个研究点目标入组 70 人开始时间: 待定最近更新: 2020年9月7日

试验速览

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•Patients with known hypertension with a blood pressure of 160/90 mm Hg or more and patients with the new-onset sever hypertention with a blood pressure of 180/110 mm Hg or more without organ damage (urgency) will be included in the study if satisfied.
•Patients between the ages of 18 and 65 will be included in the study.

•Patients who need intravenous drugs to control their blood pressure or other blood pressure medications for different reasons.
•Patients who need high dose of ACEIs or ARBs (> 50 mg/d Captopril, > 10 mg/d Enalapril, > 5 g/dLisinopril, > 50 mg/d Losartan, > 80 mg/d Valsartan),to control their blood pressure.
•Patients with myocardial infarction presenting with acute chest pain.
•Patients with severe renal or hepatic failure,anuria, papillaryedema, pulmonary edema, loss of consciousness, seizure,aortic dissection, or bilateral renal artery stenosis; pregnantpatients, patients with a history of overt allergy or angioedemawith ACEIs, Allergy to penicillins and sulfonamides.

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