IRCT20200722048172N1
Recruiting
Phase 3
Comparison and evaluation of the effectiveness of oral captopril and oral hydrochlorothiazide in the treatment of urgency hypertensive patients
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Islamic Azad University
- Enrollment
- 70
- Status
- Recruiting
- Last Updated
- 5 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients with known hypertension with a blood pressure of 160/90 mm Hg or more and patients with the new\-onset sever hypertention with a blood pressure of 180/110 mm Hg or more without organ damage (urgency) will be included in the study if satisfied.
- •Patients between the ages of 18 and 65 will be included in the study.
Exclusion Criteria
- •Patients who need intravenous drugs to control their blood pressure or other blood pressure medications for different reasons.
- •Patients who need high dose of ACEIs or ARBs (\> 50 mg/d Captopril, \> 10 mg/d Enalapril, \> 5 g/dLisinopril, \> 50 mg/d Losartan, \> 80 mg/d Valsartan),to control their blood pressure.
- •Patients with myocardial infarction presenting with acute chest pain.
- •Patients with severe renal or hepatic failure,anuria, papillaryedema, pulmonary edema, loss of consciousness, seizure,aortic dissection, or bilateral renal artery stenosis; pregnantpatients, patients with a history of overt allergy or angioedemawith ACEIs, Allergy to penicillins and sulfonamides.
Outcomes
Primary Outcomes
Not specified
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