Stress Echocardiography in Patients Recovery From Mild COVID-19 Illness
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Echocardiography, Stress
- Sponsor
- Miguel Ayala León
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- • Stroke volume
- Last Updated
- 5 years ago
Overview
Brief Summary
With the appearance of the new SARS-COV2 virus, additional challenges are being imposed on the medical community after the resolution of acute COVID-19 illness, resulting in specific pathophysiologic mechanisms that while acutely damage the lung parenchyma might chronically impact the cardiopulmonary system.
This study aims to investigate changes after mild COVID-19 illness in echocardiographic indices at rest and stress.
Investigators
Miguel Ayala León
cardiovascular critical care unit director
Hospital Beneficencia Espanola de Puebla
Eligibility Criteria
Inclusion Criteria
- •Having suffered mild COVID-19 illness
- •PCR test negative after COVID-19 illness
- •Men or women
- •Age ≥18 years and \<
- •No history of other cardiovascular or lung disease.
- •No cardiovascular risk factors, that is, arterial systemic hypertension, smoking, diabetes, dyslipidemia
- •No ongoing or previous cardio or vasoactive treatment
- •Able to use the semi-supine exercise bicycle
- •Able to give informed consent
Exclusion Criteria
- •Poor acoustic window.
- •Tricuspid regurgitation more than mild
- •Professional sports activity
- •Pregnancy
- •Obesity (body mass index \[BMI\], ≥30 kg/m2).
- •Inability to provide consent
Outcomes
Primary Outcomes
• Stroke volume
Time Frame: 3 minutes
Stroke volume
• E wave /A wave mitral
Time Frame: 3 minutes
E wave /A wave mitral
• A tricuspid (A)
Time Frame: 3 minutes
A triuspid (A)
• LV telediastolic diameter
Time Frame: 3 minutes
Left ventricle telediastolic diameter
• LV posterior wall
Time Frame: 3 minutes
Left ventricle posterior wall
• RA area
Time Frame: 3 minutes
Right atrium area
• Proximal RV outflow tract dimension at the proximal subvalvular level
Time Frame: 3 minutes
Proximal right ventricle outflow tract dimension at the proximal subvalvular level
• Inferior cava vein PW Doppler
Time Frame: 3 minutes
Inferior cava vein PW Doppler
• RV mid cavity dimension;
Time Frame: 3 minutes
Right ventricle cavity dimensión
• LA volume index
Time Frame: 3 minutes
Left atrium volume index
• Distal, RV outflow tract dimension at the distal or pulmonic valve level
Time Frame: 3 minutes
Distal, right ventricle outflow tract dimension at the distal or pulmonic valve level
• E wave mitral
Time Frame: 3 minutes
E wave mitral
• LV telesystolic diameter
Time Frame: 3 minutes
Left ventricle telesystolic diameter
• RV basal dimensión
Time Frame: 3 minutes
Right ventricle basal dimensión
• RV longitudinal dimension
Time Frame: 3 minutes
Right ventricle longitudinal dimension
• E-wave at mitral annulus
Time Frame: 3 minutes
E-wave at mitral annulus
• E-wave at mitral annulus / A-wave at the mitral annulus
Time Frame: 3 minutes
E-wave at mitral annulus / A-wave at the mitral annulus
• A wave mitral
Time Frame: 3 minutes
A wave mitral
• E tricuspid (E)
Time Frame: 3 minutes
E tricuspid (E)
• TAPSE
Time Frame: 3 minutes
• Tricuspid annular plane systolic excursion
• RV free Wall strain
Time Frame: 3 minutes
Right ventricle free Wall strain
• E/A
Time Frame: 3 minutes
E/A
• E wave/ E-wave at the mitral annulus
Time Frame: 3 minutes
E wave/ E-wave at the mitral annulus
• E-wave at the tricuspid annulus
Time Frame: 3 minutes
E-wave at the tricuspid annulus
• Cardiac output
Time Frame: 3 minutes
Cardiac output
• Systolic pulmonary artery pressure
Time Frame: 3 minutes
Systolic pulmonary artery pressure
• Mean pulmonary artery pressure
Time Frame: 3 minutes
Mean pulmonary artery pressure