Stress Echocardiography in Patients Recovery From Mild COVID-19 Illness
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- • Stroke volume
研究概览
简要总结
With the appearance of the new SARS-COV2 virus, additional challenges are being imposed on the medical community after the resolution of acute COVID-19 illness, resulting in specific pathophysiologic mechanisms that while acutely damage the lung parenchyma might chronically impact the cardiopulmonary system.
This study aims to investigate changes after mild COVID-19 illness in echocardiographic indices at rest and stress.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Having suffered mild COVID-19 illness
- •PCR test negative after COVID-19 illness
- •Men or women
- •Age ≥18 years and <
- •No history of other cardiovascular or lung disease.
- •No cardiovascular risk factors, that is, arterial systemic hypertension, smoking, diabetes, dyslipidemia
- •No ongoing or previous cardio or vasoactive treatment
- •Able to use the semi-supine exercise bicycle
- •Able to give informed consent
排除标准
- •Poor acoustic window.
- •Tricuspid regurgitation more than mild
- •Professional sports activity
- •Pregnancy
- •Obesity (body mass index [BMI], ≥30 kg/m2).
- •Inability to provide consent
结局指标
主要结局
• Stroke volume
时间窗: 3 minutes
Stroke volume
• E wave /A wave mitral
时间窗: 3 minutes
E wave /A wave mitral
• A tricuspid (A)
时间窗: 3 minutes
A triuspid (A)
• LV telediastolic diameter
时间窗: 3 minutes
Left ventricle telediastolic diameter
• LV posterior wall
时间窗: 3 minutes
Left ventricle posterior wall
• RA area
时间窗: 3 minutes
Right atrium area
• Proximal RV outflow tract dimension at the proximal subvalvular level
时间窗: 3 minutes
Proximal right ventricle outflow tract dimension at the proximal subvalvular level
• Inferior cava vein PW Doppler
时间窗: 3 minutes
Inferior cava vein PW Doppler
• RV mid cavity dimension;
时间窗: 3 minutes
Right ventricle cavity dimensión
• LA volume index
时间窗: 3 minutes
Left atrium volume index
• Distal, RV outflow tract dimension at the distal or pulmonic valve level
时间窗: 3 minutes
Distal, right ventricle outflow tract dimension at the distal or pulmonic valve level
• E wave mitral
时间窗: 3 minutes
E wave mitral
• LV telesystolic diameter
时间窗: 3 minutes
Left ventricle telesystolic diameter
• RV basal dimensión
时间窗: 3 minutes
Right ventricle basal dimensión
• RV longitudinal dimension
时间窗: 3 minutes
Right ventricle longitudinal dimension
• E-wave at mitral annulus
时间窗: 3 minutes
E-wave at mitral annulus
• E-wave at mitral annulus / A-wave at the mitral annulus
时间窗: 3 minutes
E-wave at mitral annulus / A-wave at the mitral annulus
• A wave mitral
时间窗: 3 minutes
A wave mitral
• E tricuspid (E)
时间窗: 3 minutes
E tricuspid (E)
• TAPSE
时间窗: 3 minutes
• Tricuspid annular plane systolic excursion
• RV free Wall strain
时间窗: 3 minutes
Right ventricle free Wall strain
• E/A
时间窗: 3 minutes
E/A
• E wave/ E-wave at the mitral annulus
时间窗: 3 minutes
E wave/ E-wave at the mitral annulus
• E-wave at the tricuspid annulus
时间窗: 3 minutes
E-wave at the tricuspid annulus
• Cardiac output
时间窗: 3 minutes
Cardiac output
• Systolic pulmonary artery pressure
时间窗: 3 minutes
Systolic pulmonary artery pressure
• Mean pulmonary artery pressure
时间窗: 3 minutes
Mean pulmonary artery pressure
次要结局
未报告次要终点
研究者
Miguel Ayala León
cardiovascular critical care unit director
Hospital Beneficencia Espanola de Puebla