Assessment of Heart function and volume during Heart surgery using echocardiographic contrast agent.
- Conditions
- Health Condition 1: I25- Chronic ischemic heart disease
- Registration Number
- CTRI/2024/04/065434
- Lead Sponsor
- Sree Chitra Tirunal Institute for Medical Sciences and Technology,Trivandrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
All Adult patients scheduled for elective coronary artery bypass grafting
Normal sinus rhythm.
Emergency surgeries
Redo surgeries
Patients not willing to participate in study
More than mild AR, MR or TR
Any allergies to the contrast agents
Contraindications for SonoVue administration (as recommended by the manufacturers)-Unstable coronary artery disease, acute Cardiac failure, right to Left shunts, severe pulmonary arterial htn (RVSP > 55mmHg on TTE).
Patient with arrhythmias.
Contraindication to TEE probe placement like esophageal strictures, esophageal varices, esophageal tumors, gastric ulcer, previous esophagectomy, esophageal diverticulum, tracheoesophageal fistula, previous bariatric surgery, hiatus hernia, large descending thoracic aortic aneurysm, unilateral vocal cord paralysis, esophageal varices, post-radiation therapy.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate whether injection of echo contrast increases the estimated LV volumes on 2D echocardiography compared to those without the use of contrast.Timepoint: after induction of anaesthesia, before going on cardiopulmonary bypass.
- Secondary Outcome Measures
Name Time Method To compare intra-observer and inter-observer variability in the measurement of LV volumes with and without echo contrast.Timepoint: after induction of anaesthesia, before going on cardiopulmonary bypass.;To compare static cardiac output measured by Modified Simpson’s method with or without echo contrast with LVOT dynamic cardiac output.Timepoint: after induction of anaesthesia, before going on cardiopulmonary bypass.;To evaluate whether the echo contrast increases the 3D echocardiographic estimation of LV volumesTimepoint: after induction of anaesthesia, before going on cardiopulmonary bypass.