Prospective Data Collection of Elderly Patients With DLBCL Receiving at the Time of Diagnosis VGM
- Conditions
- Lymphoma, Large B-Cell, Diffuse
- Registration Number
- NCT02364050
- Lead Sponsor
- Fondazione Italiana Linfomi - ETS
- Brief Summary
Prospective data collection of a consecutive series of elderly patients with large B-cell lymphoma newly diagnosed, receiving before the start of treatment Multidimensional Geriatric Assessment (VGM) through the use of Activity of Daily Living (ADL), Instrumental Activity of Daily Living (IADL) and Cumulative Illness Rating Scale for Geriatrics (CIRS-G).
- Detailed Description
Prospective data collection of a consecutive series of elderly patients with large B-cell lymphoma newly diagnosed, receiving before the start of treatment Multidimensional Geriatric Assessment (VGM) through the use of Activity of Daily Living (ADL), Instrumental Activity of Daily Living (IADL) and Cumulative Illness Rating Scale for Geriatrics (CIRS-G) to be defined in 3 categories:
* elderly FIT (ADL 6; IADL 8; 0 score= 3-4, \< 5 score=2)
* elderly UNIFIT (ADL 5; IADL 6-7; 0 score= 3-4, 5-8 score=2; ≥ 80 fit)
* elderly FRAIL (ADL ≤ 4; IADL ≤ 5; 1 score= 3-4, \> 8 score=2; ≥ 80 unfit)
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 1300
- Patient with Large B-cell Lymphoma
- Age ≥ 65 years
- informed Consent
- Violation of inclusion criteria
- Abscence of data considered essential for the study
- Withdrawal of Consent
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method OS 5 years Overall survival
- Secondary Outcome Measures
Name Time Method PFS 5 years Progression free survival
Early mortality rate 5 years % of patients who performed pre-phase therapy 5 years Come to the prefect Therapy is a steroid-based therapy (administered at dosage of at least 25 mg / day) and / or vincristine, which precedes the beginning of the program of chemoimmunotherapy.
Response to initial therapy 5 years FFS 5 years Failure Free Survival
Trial Locations
- Locations (55)
Azienda Ospedaliera Caravaggio
🇮🇹Treviglio, Bergamo, Italy
A.O.Cardinale Panico Ematologia e centro trapianti
🇮🇹Tricase, LE, Italy
IRCCS Humanitas
🇮🇹Rozzano, Milano, Italy
CRO-Centro di Riferimento Oncologico
🇮🇹Aviano, Pordenone, Italy
CROB
🇮🇹Rionero in Vulture, Potenza, Italy
Polo Pontino
🇮🇹Latina, Roma, Italy
ASL TO-4
🇮🇹Ivrea, Torino, Italy
Ospedale S. Giacomo di Castelfranco Veneto
🇮🇹Castelfranco Veneto, Treviso, Italy
AO SS.Antonio e Biagio
🇮🇹Alessandria, Italy
AOU Ospedali Riuniti
🇮🇹Ancona, Italy
Scroll for more (45 remaining)Azienda Ospedaliera Caravaggio🇮🇹Treviglio, Bergamo, Italy