Prospective Data Collection of Elderly Patients (≥ 65 Years) With Diffuse Large B-cell Lymphoma (DLBCL) Receiving at the Time of Diagnosis Multidimensional Geriatric Assessment (VGM)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lymphoma, Large B-Cell, Diffuse
- Sponsor
- Fondazione Italiana Linfomi - ETS
- Enrollment
- 1300
- Locations
- 55
- Primary Endpoint
- OS
- Last Updated
- 6 years ago
Overview
Brief Summary
Prospective data collection of a consecutive series of elderly patients with large B-cell lymphoma newly diagnosed, receiving before the start of treatment Multidimensional Geriatric Assessment (VGM) through the use of Activity of Daily Living (ADL), Instrumental Activity of Daily Living (IADL) and Cumulative Illness Rating Scale for Geriatrics (CIRS-G).
Detailed Description
Prospective data collection of a consecutive series of elderly patients with large B-cell lymphoma newly diagnosed, receiving before the start of treatment Multidimensional Geriatric Assessment (VGM) through the use of Activity of Daily Living (ADL), Instrumental Activity of Daily Living (IADL) and Cumulative Illness Rating Scale for Geriatrics (CIRS-G) to be defined in 3 categories: * elderly FIT (ADL 6; IADL 8; 0 score= 3-4, \< 5 score=2) * elderly UNIFIT (ADL 5; IADL 6-7; 0 score= 3-4, 5-8 score=2; ≥ 80 fit) * elderly FRAIL (ADL ≤ 4; IADL ≤ 5; 1 score= 3-4, \> 8 score=2; ≥ 80 unfit)
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient with Large B-cell Lymphoma
- •Age ≥ 65 years
- •informed Consent
Exclusion Criteria
- •Violation of inclusion criteria
- •Abscence of data considered essential for the study
- •Withdrawal of Consent
Outcomes
Primary Outcomes
OS
Time Frame: 5 years
Overall survival
Secondary Outcomes
- PFS(5 years)
- Response to initial therapy(5 years)
- FFS(5 years)
- Early mortality rate(5 years)
- % of patients who performed pre-phase therapy(5 years)