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Clinical Trials/NCT06002763
NCT06002763
Recruiting
Not Applicable

Evaluation of Patient-Reported Outcomes Measurement Information System (PROMIS)-29 v2.1 for Postpartum Women

Samuel Lunenfeld Research Institute, Mount Sinai Hospital1 site in 1 country200 target enrollmentJuly 9, 2025

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Well-Being, Psychological
Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Enrollment
200
Locations
1
Primary Endpoint
PROMIS-29 v2.1 (Patient-Reported Outcomes Measurement Information System) survey score
Status
Recruiting
Last Updated
9 months ago

Overview

Brief Summary

There is no widely used, statistically validated assessment for physical and mental health for the short- to medium-term in a postpartum population. PROMIS-29 has been validated for the assessment of these factors in a generic population, but has not been specifically evaluated for use with postpartum women.

This study is a longitudinal, single center observational cohort study designed to evaluate the reliability of the Patient-Reported Outcomes Measurement Information System (PROMIS)-29 v2.1 survey in a postpartum population. PROMIS-29 is a survey designed to screen for pain, impairments in mood, physical function, and activities of daily living. While this survey has shown utility in other populations, it has yet to be assessed in an obstetric population. The investigators plan to recruit patients who are recently postpartum from vaginal or cesarean delivery to complete virtual surveys at defined time points (0, 2, 6, and 12 weeks after delivery). The investigators will subject survey data to statistical measures of validity and reliability comparing with contemporaneously collected surveys of established metrics for quality of life (WHOQoLBREF) and general (global) state of health (numerical rating score 1-100).

The hypothesis is that the PROMIS-29 v2.1 questionnaire is a statistically valid and reliable means of assessing physical and mental health in a postpartum population.

Registry
clinicaltrials.gov
Start Date
July 9, 2025
End Date
July 1, 2026
Last Updated
9 months ago
Study Type
Observational
Sex
Female

Investigators

Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 18 years old and over
  • singleton births
  • 37 or more weeks gestational age
  • multiparous or nulliparous patients
  • spontaneous vaginal delivery or scheduled cesarean delivery with labor analgesia or neuraxial anesthesia
  • give informed written consent

Exclusion Criteria

  • refusal to take part
  • are unable to give or have withdrawn consent
  • patients unable to communicate fluently in English
  • patients who are less than 18 years old
  • patients who had fetal demise or severely morbid fetal conditions such as intubation, cooling, expected surgical correction of congenital anomaly during hospitalization (although NICU admissions will be included)
  • patients who were admitted in ICU
  • patients who had failed neuraxial analgesia such as replaced epidurals or failed spinal requiring conversion to general anesthesia
  • patients who had general anesthesia for cesarean delivery as defined by "GETA", including sedatives and deep sedation if not intubated
  • patients who had intrapartum cesarean or had assisted/operative (i.e. vacuum, forceps) vaginal delivery.

Outcomes

Primary Outcomes

PROMIS-29 v2.1 (Patient-Reported Outcomes Measurement Information System) survey score

Time Frame: 12 weeks

The PROMIS survey score at 12 weeks postpartum

WHOQoLBREF (World Health Organization Quality of Life Brief Version) survey score

Time Frame: 12 weeks

The WHOQoLBREF survey score at 12 weeks postpartum

EQ-5D-3L1 (not an acronym) survey score

Time Frame: 12 weeks

The EQ-5D-3L1 survey score at 12 weeks postpartum

Study Sites (1)

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