Effect of Busulfan in left ventricular global lingitudinal strai
Phase 2
- Conditions
- Cardiomyopathy.Cardiomyopathy
- Registration Number
- IRCT20191230045950N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Patients undergoing allogenic bone marrow transplantation
Exclusion Criteria
Diabetes melitus
Hypertension
Smoking
Family history of Ischemic heart disease
Major valvular heart disease
Hyperlipidemia
CKD
Obesity
Initial ejection fraction less than 55%
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eft ventricular function by Global longitudinal strain (GLS). Timepoint: At the begining of the study and 7 days after Busulfan therapy. Method of measurement: Echocardiography.
- Secondary Outcome Measures
Name Time Method eft ventricular end diastolic volume. Timepoint: At the begining and 7 days after Busulfan therapy. Method of measurement: Echocardoography.;Left ventricular end systolic volume. Timepoint: At the begining and 7 days after Busulfan therapy. Method of measurement: Echocardiography.;Left ventricular ejection fraction. Timepoint: At the begining and 7 days after Busulfan therapy. Method of measurement: Echocardiograghy.