The Effect of Different Gingival Biotypes on Dimensional Stability of Free Gingival Graft

Not Applicable

Completed

• Conditions: Atrophy; Gingival Recession
• Interventions: Procedure: free gingival graft

• Registration Number: NCT03616197
• Lead Sponsor: Istanbul Aydın University

Brief Summary

The aim of this study is to compare the effect of mesial and distal adjacent gingival biotypes of the tooth / teeth region of free gingival graft (FGG) on the shrinkage ratio of graft at 6 months postoperatively.

Detailed Description

The concept of gingival and periodontal phenotype was established as a result of clinical observation of changes in facial keratinized tissue width and thickness .It has been reported that gingival or periodontal diseases may develop more frequently in patients with thin gingival biotypes and that thick-flat biotype in implant restorations is important in achieving a successful aesthetic treatment outcome.

Free gingival graft (FGG) is a mucogingival surgical procedure that is successfully used in the presence of inadequate keratinized gingival width and gingival recession. It is thought that factors that may adversely affect the continuity of graft nutrition may be effective in graft shrinkage. These reasons can be listed as follows; graft thickness, traumatic surgical procedure, graft dehydration, and suturing procedure.

There was no study investigating the effect of periodontal biotypes on graft contraction in the region adjacent to the FGG operation.

Study Timeline

• Study Start: 2016-08
• Primary Completion: 2018-04
• Study Completion: 2018-07
• Study First Submitted: 2018-07-31
• Study First Submitted QC: 2018-07-31
• Status Verified: 2018-08
• Study First Posted: 2018-08-06
• Last Update Submitted: 2018-08-07
• Last Update Posted: 2018-08-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• In the mandibular incisor tooth / teeth, the attached keratinized gingival width is <1 mm,
• No periodontal surgery has been performed previously on the involved tooth.
• In the absence of any systemic condition or illness (pregnancy, breastfeeding, mental retardation, diabetes, etc.) that may interfere with the patient's approval and dental treatment.
• Do not use any of the drug groups that may cause gingival overgrowth.

Exclusion Criteria

• Previous periodontal surgery in the operation area
• Restoration of the buccal surface of the tooth and no pathology in the apical region of the tooth.
• In the presence of any systemic condition or illness (pregnancy, breastfeeding, mental retardation, diabetes, etc.) that may interfere with the patient's approval and dental treatment.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group 1	free gingival graft	Thin Biotype group has described as Group 1. The biotypes of the terminal teeth adjacent to the free gingival graft region were determined by the "Probe transparency method". The mesial terminal tooth (MTT) was defined as the first tooth adjacent to the mesial side of the tooth / teeth to which the FGG will be applied. The distal terminal tooth (DTT) was defined as the first tooth adjacent to the distal side of the tooth / teeth to which the FGG will be applied. If MTT and DTT had thin biotype, the patient was assigned to the thin biotype group.
Group 2	free gingival graft	Thick biotype group has described as Group 2. The biotypes of the terminal teeth adjacent to the free gingival graft region were determined by the "Probe transparency method". The mesial terminal tooth (MTT) was defined as the first tooth adjacent to the mesial side of the tooth / teeth to which the FGG will be applied. The distal terminal tooth (DTT) was defined as the first tooth adjacent to the distal side of the tooth / teeth to which the FGG will be applied. If MTT and DTT had thick biotype, the patient was assigned to the thick biotype group.

Primary Outcome Measures

Name	Time	Method
The graft shrinkage ratio	baseline - 6th months postoperatively	Graft shrinkage = Preoperative area - Postoperative area X 100 Preoperative area

Secondary Outcome Measures

Name	Time	Method
keratinized ginigival width	baseline - 6th months postoperatively	Keratinized Gingival Width(KGW) was measured using a lugol solution (10% potassium iodide and 5% iodine) with a manual caliper spaced 0.5 mm from the mid-buccal point of the tooth, the distance between the gingival margin and mucogingival junction from MTT, DTT and the teeth/tooth in operation area.