NCT05815043已完成不适用
Effects of Sodium Intake on Arterial Stiffness in Black Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 34
- 试验地点
- 2
- 主要终点
- Cardio-ankle vascular index
研究概览
简要总结
The purpose of this study is to explore the influence of sodium intake on arterial stiffness in African American/Black adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Sequential
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •African American or Black
- •Male or Female
排除标准
- •pregnancy or within 60 days postpartum
- •having taken blood pressure (including diuretics beta-blockers, ACE inhibitors, angiotensin receptor blockers, and calcium channel blockers) or statin medications within the past 3 months
- •infection (viral or other) within the past 4 weeks
- •having adrenal or endocrine tumors (these could impact BP)
- •renal disease defined as a glomerular filtration rate (GFR) of less than 60
- •prior myocardial infarction
- •known coronary heart disease
- •personal history of stroke
- •heart failure
- •cardiac arrhythmias
- •recent chest pain or dyspnea
- •current insulin dependence
- •currently undergoing chemotherapy or radiation
- •identifying as transgender (the focus of this trial is biological sex)
- •seated systolic or diastolic blood pressure of more than 149 mm Hg or 99 mm Hg, respectively
结局指标
主要结局
Cardio-ankle vascular index
时间窗: This measurement will take approximately 1 minute and will be completed twice.
Cardio-ankle vascular index will be assessed using simultaneous arm and ankle blood pressures, EKG, and phonocardiography
Ambulatory blood pressure
时间窗: This measurement will take approximately 24 hours and will be obtained from the date of enrollment until the date of completion of the study up to 10 days after enrollment.
24-hour ambulatory blood pressure monitoring will be completed on day 3 of each dietary condition.
次要结局
- Renal sodium excretion(This measurement will be obtained from the date of enrollment until the date of completion of the study up to 10 days after enrollment.)
研究者
研究点 (2)
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