Effects of Sodium Intake on Arterial Stiffness in Black Adults

Texas State University1 site in 1 country34 target enrollmentDecember 13, 2022

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Not specified
Sponsor: Texas State University
Enrollment: 34
Locations: 1
Primary Endpoint: Cardio-ankle vascular index
Status: Completed
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to explore the influence of sodium intake on arterial stiffness in African American/Black adults.

Registry

clinicaltrials.gov

Start Date

December 13, 2022

End Date

December 30, 2023

Last Updated

last year

Study Type

Interventional

Study Design

Sequential

Sex

All

Investigators

Sponsor

Texas State University

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•African American or Black
•Male or Female

Exclusion Criteria

•pregnancy or within 60 days postpartum
•having taken blood pressure (including diuretics beta-blockers, ACE inhibitors, angiotensin receptor blockers, and calcium channel blockers) or statin medications within the past 3 months
•infection (viral or other) within the past 4 weeks
•having adrenal or endocrine tumors (these could impact BP)
•renal disease defined as a glomerular filtration rate (GFR) of less than 60
•prior myocardial infarction
•known coronary heart disease
•personal history of stroke
•heart failure
•cardiac arrhythmias

Outcomes

Primary Outcomes

Cardio-ankle vascular index

Time Frame: This measurement will take approximately 1 minute and will be completed twice.

Cardio-ankle vascular index will be assessed using simultaneous arm and ankle blood pressures, EKG, and phonocardiography

Ambulatory blood pressure

Time Frame: This measurement will take approximately 24 hours and will be obtained from the date of enrollment until the date of completion of the study up to 10 days after enrollment.

24-hour ambulatory blood pressure monitoring will be completed on day 3 of each dietary condition.

Secondary Outcomes

Renal sodium excretion(This measurement will be obtained from the date of enrollment until the date of completion of the study up to 10 days after enrollment.)