Attention Bias Modification (ABM) for Major Depressive Disorder

Completed

• Conditions: Major Depressive Disorder (MDD)

• Registration Number: NL-OMON24957
• Lead Sponsor: Pro Persona, Center for Mental Health Care, Nijmegen, The NetherlandsWolfheze 2, 6874 Wolfheze

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 126

Inclusion Criteria

•A diagnosis of major depressive disorder, first or recurrent according to the DSM- IV-TR, as assessed with the MINI Neuropsychiatric Interview

•Age: between 18-65 years

Exclusion Criteria

•Any psychotic disorder (current or previous)

•Current mania or hypomania or a history of bipolar disorder

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
•Attentional bias (dot-probe task)<br /><br>•Depression level as assessed by the Inventory of Depressive Symptomatology self-report (IDS-SR)<br /><br>•Emotional vulnerability in response to a speech task as measured by the Spielberger State Anxiety Inventory (STAI-S) and the Positive and Negative Affect Scale (PANAS)<br>

Secondary Outcome Measures

Name	Time	Method
•Attentional control, as measured by the classical Stroop task <br /><br>•Attentional bias for verbal positive and negative information (‘emotional Stroop task’), <br /><br>•Ruminative Response Scale (RRS-NL) <br /><br>•Positive and Negative Affect (PANAS)<br /><br>•Prospective Imagery Task (PIT) <br /><br>•Resilience Scale (RS) <br /><br>•Number of sessions of out-patient therapy needed <br /><br>•Credibility/Expectancy Questionnaire (CEQ) <br /><br>•Quality of life (EuroQol; EQ-5D) and costs/ health care utilization (Trimbos/iMTA questionnaire; TicP) <br /><br>•Diagnostic status of depression according to the DSM-IV-TR as assessed by the MINI Neuropsychiatric Interview