NL-OMON47931
Recruiting
Not Applicable
Platelet RNA profiling to screen for cancer in patients with unprovoked venous thromboembolism - Tumour-educated platelets in venous thromboembolism
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- venous thromboembolism
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 270
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- First, objectively confirmed, symptomatic, unprovoked symptomatic pulmonary
- •embolism and/or distal or proximal deep vein thrombosis of the leg
- •\- Age 40 years or older
- •\- Written informed consent
Exclusion Criteria
- •\- One or more of the following risk factors for veneuze trombo\-embolie (VTE):
- •\- known malignant disease prior to VTE defined as a cancer diagnosis or
- •cancer treatment within the past 5 years;
- •\- trauma or fracture of the leg, surgical procedures, general anesthesia, or
- •immobilization greater than 3 days within previous 3 months;
- •\- previous unprovoked venous thromboembolism;
- •\- known hereditary or acquired thrombophilia;
- •\- current pregnancy or puerperium (up to 3 months postpartum);
- •\- current estrogen therapy.
- •\- Greater than 10 days after VTE diagnosis;
Outcomes
Primary Outcomes
Not specified
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