EUCTR2020-001431-27-DE
进行中(未招募)
1 期
Treatment of Sars-CoV2 infections (Covid-19) in patients without or with chronic kidney disease (CKD) with valsartan vs placebo, a three-armed randomized, partly blinded trial
概览
- 阶段
- 1 期
- 干预措施
- 未指定
- 疾病 / 适应症
- Sars-Cov2 infection
- 发起方
- Klinikum St. Georg gGmbH
- 入组人数
- 300
- 状态
- 进行中(未招募)
- 最后更新
- 4年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •\- Patients aged over 18 years with given consent, first positive Sars\-Cov2 detection within the last three days
- •\- Patients with pre\-existing chronic renal insufficiency in any degree of severity
- •\- Patients of both gender
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range 200
- •F.1\.3 Elderly (\>\=65 years) yes
- •F.1\.3\.1 Number of subjects for this age range 100
排除标准
- •\- intolerance to RAS\-I and ARB
- •\- Contraindications against ACE/ARB according to current clinical standard
- •\- History of falls (more than 2 falls in the last 8 weeks)
- •\- Symptomatic hypotension (i.e. blood pressure \< 100 mmHg systolic and/or 50 mmHg diastolic together with hypotensive symptoms)
- •\- Acute renal failure from stage 2
- •\- pregnancy
结局指标
主要结局
未指定
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