Hyaluronic Acid as Adjunctive to Chlorhexidine Mouthwash for Gingivitis: RCT
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 16
- 试验地点
- 1
- 主要终点
- Bleeding on probing
研究概览
简要总结
Patients were instructed to use 2 different mouthwashes after performing professional tooth cleaning. The effect of each of the 2 mouthwashes was detected.
详细描述
The study tests the efficacy of hyaluronic acid (HYL) mouthwash as adjunct to Chlorhexidine (CHX) mouthwash compared to Chlorhexidine mouthwash only in 16 gingivitis patients. Patients were randomly assigned to either control group received (Chlorhexidine mouthwash) or test group received (hyaluronic acid + Chlorhexidine mouthwash). Clinical parameters and patient reported outcomes as post-operative questionnaire were assessed at baseline and seven days post-operatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with gingivitis
排除标准
- •pregnant or lactating females and current smokers
研究组 & 干预措施
Chlorhexidine mouthwash
干预措施: Chlorhexidine 0,12% (Drug)
Hyaluronic acid + Chlorhexidine mouthwash
干预措施: Hyaluoric acid mouthwash (Drug)
Hyaluronic acid + Chlorhexidine mouthwash
干预措施: Chlorhexidine 0,12% (Drug)
结局指标
主要结局
Bleeding on probing
时间窗: 7 days
% of gingival sites where bleeding occurred on periodontal probing is registered out of total gingival sites
次要结局
- Plaque index(7 days)
- Patient's satisfaction questionnaire(7 days)