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Clinical Trials/NCT07606781
NCT07606781RecruitingNot Applicable

Analgesic Effect of Combination of Superior Hypogastric Plexus Block and Transversus Abdominis Plane Block in Abdominal Hysterectomies: A Randomized Controlled Trial

Tanta University1 site in 1 country44 target enrollmentStarted: May 23, 2026Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Enrollment
44
Locations
1

Study Overview

Brief Summary

This study aims to evaluate the analgesic effect of superior hypogastric plexus block combined with transversus abdominis plane block in abdominal hysterectomies.

Detailed Description

Abdominal hysterectomy is a major surgery that is often associated with pronounced postsurgical pain. Inadequate postoperative analgesia can lead to postoperative complications and can delay functional recovery. Accordingly, a multimodal regimen for postoperative pain management is recommended.

The transverse abdominis plane (TAP) block is a regional block anesthetizing the nerves (T10 to L1) hence covering the lower abdominal wall.

The superior hypogastric plexus (SHP), which lies retroperitoneally in front of the L5 and S1 vertebrae, provides innervation to the pelvic viscera. The blockade of SHP is well-recognized for the management of chronic pelvic pain.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
Female
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age ≥ 18 years.
  • American Society of Anesthesiology (ASA) physical status I-II.
  • Undergoing abdominal hysterectomies under general anesthesia (GA).

Exclusion Criteria

  • History of allergies to local anesthetics.
  • Body mass index (BMI) >35 kg/m
  • Opioid dependency.
  • Cognitive impairment.
  • Bleeding or coagulation disorders.
  • Psychiatric and neurological disorder.
  • Local infection at the site of injection.
  • Severe heart, lung, liver, and renal dysfunction.

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Mohammed Said ElSharkawy

Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Tanta University

Study Sites (1)

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