The effect of Pioglitazone on vascular and ventricular function in people with type 2 diabetes PICCOLA - PICCOLA

Phase 1

• Conditions: Diabetes; MedDRA version: 9.1Level: LLTClassification code 10012601Term: Diabetes mellitus; MedDRA version: 9.1Level: LLTClassification code 10012613Term: Diabetes mellitus non-insulin-dependent; MedDRA version: 9.1Level: LLTClassification code 10045242Term: Type II diabetes mellitus

• Registration Number: EUCTR2007-001222-27-GB
• Lead Sponsor: Imperial College London

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-05-30
• Study Completion: 2010-04-01
• Last Update Posted: 13 October 2020

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Male and female type 2 diabetics of any age will be included. There is a wide inclusion criteria to reflect that the 24 participants are a random sample representative of the diabetic clinic attendees.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Subjects will be excluded if they have any of the following:

Known coronary heart disease
Patients receiving Insulin
Uncontrolled hypertension (i.e. >160mmHg systolic or >95mmHg diastolic)
Systolic dysfunction (ejection fraction <50%)
Heart Valve Disease
Proliferative or pre-proliferative retinopathy
Severe hepatic or renal impairment
Possible pregnancy
Malignancy

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified