Detection of prognostic biomarkers in patients with oral squamous cell carcinoma with tissue microarray

• Conditions: Oral Squamous Cell Carcinoma; C01; C02; C03; C04; C05; C06; Malignant neoplasm of base of tongue; Malignant neoplasm of other and unspecified parts of tongue; Malignant neoplasm of gum

• Registration Number: DRKS00010431
• Lead Sponsor: niversitätsklinikum Hamburg-Eppendorf

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11-25
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

18 years of age, histologically proven primary oral squamous cell carcinoma starting from 2005 or later, known TNM-status, sufficient diameter of tumor embedded in paraffin, informed consent

Exclusion Criteria

<18 years of age, no informed consent, not enough tumor (<5mm diameter) embedded in paraffin, no tam status

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Detection of prognostic biomarkers with tissue microarray for the outcome in patients with OSCC

Secondary Outcome Measures

Name	Time	Method
Risk Factors alcohol, nicotine and drugs, nutrition, oral health status, TNM-classification, HPV-status, sex, age, date of recurrent cancer, type and duration of surgical and adjuvant oncological therapy, functional outcome, date of death, cause of death, oral hygiene.