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Clinical Trials/NCT05067426
NCT05067426CompletedNot Applicable

The 10/7 HIIT Shock Cycle Study: The Effects of a 7-Day High-Intensity-Interval Training Shock Microcycle on Endurance Performance, Well-Being, Stress and Recovery in Endurance Trained Athletes - Randomized Controlled Trial

University of Salzburg1 site in 1 country33 target enrollmentStarted: August 15, 2021Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
33
Locations
1
Primary Endpoint
Endurance performance I

Study Overview

Brief Summary

A randomized, controlled trial to evaluate the effects of two versions of 10 high intensity interval trainings (HIIT) within a 7-day shock microcycle on endurance performance, well-being, health, stress and recovery in trained athletes.

Detailed Description

Thirty-six trained endurance athletes will be recruited and randomly assigned to either a "high volume (HIIT-HV)" group, a "low volume (HIIT-LV)" group, or a control group. All participants will be monitored before (9 days), during (7 days), and after (14 days) a 7-day training intervention, for 30 days. Participants in both intervention groups will complete 10 HIIT sessions within the period of 7 days, with an additional 30 minutes of low-intensity training exclusively in HIIT-HV. HIIT sessions consist of aerobic HIIT, i.e., 5x4min at 90-95% of maximal heart rate interspersed by 2.5 min active recovery periods. To determine the effects of the intervention, performance diagnostics, and a 5 kilometer time trial will be conducted before and after the intervention. In addition, participants are closely monitored for general health, stress, fatigue, recovery, neuromuscular performance, executive functions and sleep.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to 45 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Female or male
  • •aged 18-45 years
  • •Proof of physical fitness (e.g. sports medical examination required) for measurements with higher intensities (e.g. endurance tests, competition simulation)
  • •Competition experience at the national or international level in an endurance sport
  • •VO2max ≥50ml/kg/min for females; ≥55 ml/kg/min for males or a 5-kilometer (km) time trial performance of ≤ 20:00 min (female), or ≤ 18:30 min (male)

Exclusion Criteria

  • •Systemic disease or other known pathology in the organs: heart, lungs, kidney, stomach, spleen, liver, gall bladder, and intestines.
  • •Evidence of pulmonary disease: forced expiratory volume in one second/forced expiratory volume < 70% with/without symptoms (cough, sputum) or other evidence of pulmonologic disease.
  • •Diabetes II.
  • •Neurological or psychological disease of any kind.
  • •Currently undergoing medical or psycho-therapeutic treatment.
  • •Health condition that does not allow regular participation in the training forms (e.g. acute illnesses such as fever or other flu-like infections within the last 7 days before the start of the study), orthopedic diseases, injuries to the muscular, bone, joint or tendon apparatus within the last three months.
  • •Alcohol or drug abuse.
  • •Already high training volume with high intensity training (more than 2 weekly training sessions of high-intensity training)

Arms & Interventions

HIIT-HV

Experimental

HIIT-HV - high intensity interval training high volume

Participants complete a total of 10 HIIT sessions over a 7-day period consisting of 5 x 4-minute intervals at an intensity of 90-95% of their individual maximum heart rate (HRmax), interspersed with a 2.5-minute active recovery period. Each training session is followed by 30 minutes of low-intensity training (total of 300 minutes of additional low-intensity training during this period).

Intervention: Exercise (Other)

HIIT-LV

Experimental

HIIT- LV - high intensity interval training low volume

Participants complete a total of 10 HIIT sessions over a 7-day period consisting of 5 x 4-minute intervals at an intensity of 90-95% of their individual maximum heart rate (HRmax), interspersed with a 2.5-minute active recovery period.

Intervention: Exercise (Other)

Control group

No Intervention

Participants continue with their regular training program.

Outcomes

Primary Outcomes

Endurance performance I

Time Frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)

Change of maximal oxygen uptake (VO2max in ml/min/kg) compared to baseline and group

Endurance performance III

Time Frame: 20 to 22 days (the assessment is conducted once before, and once after the intervention)

Change of 5 kilometer time trial performance (in sec) compared to baseline and group

Endurance performance IV

Time Frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)

Change of lactate threshold (in km/h) compared to baseline and group

Endurance performance II

Time Frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)

Change of peak performance (Ppeak in Watt) compared to baseline and group

Endurance performance V

Time Frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)

Change of ventilatory thresholds (in km/h) compared to baseline and group

Endurance performance VI

Time Frame: 10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention)

Change of running economy (in ml/min/kg) compared to baseline and group

Secondary Outcomes

  • Change of questionnaire scores - well-being(30 days (questionnaires will be given to participants several times before, during, and after the intervention.))
  • Change of forced expiratory volume(10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention))
  • Change of executive functions - 2 back task(30 days (executive functions are tested several times before, during, and after the intervention))
  • Adherence to training program(7 days)
  • Change of questionnaire scores - rate of fatigue(30 days (questionnaires will be given to participants several times before, during, and after the intervention.))
  • Change of questionnaire scores - sleep quality(30 days (questionnaires will be given to participants several times before, during, and after the intervention.))
  • Change of urea(30 days (blood is drawn from participants several times before, during, and after the intervention.))
  • Change of miRNA(30 days (blood is drawn from participants several times before, during, and after the intervention.))
  • Change of sleep quality I - GPS watch(30 days (sleep is assessed several times before, during, and after the intervention))
  • Change of questionnaire scores - vitality(30 days (questionnaires will be given to participants several times before, during, and after the intervention.))
  • Change of blood count(30 days (blood is drawn from participants several times before, during, and after the intervention.))
  • Change of cell-free DNA(30 days (blood is drawn from participants several times before, during, and after the intervention.))
  • Change of fat free mass(10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention))
  • Change of power output during exercise(7 days)
  • Change of sleep quality II - ABIOS App(30 days (sleep is assessed several times before, during, and after the intervention))
  • Change of blood lactate(30 days (blood is drawn from participants several times before, during, and after the intervention.))
  • Change of neuromuscular performance(30 days (neuromuscular performance is assessed several times before, during, and after the intervention))
  • Change of body weight(10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention))
  • Change of parameters recorded by an electrocardiogram - mean heart rate(30 days (an electrocardiogram is written several times before, during, and after the intervention))
  • Change of parameters recorded by an electrocardiogram - heart rate variability(30 days (an electrocardiogram is written several times before, during, and after the intervention))
  • Cardiac ultrasound(1 day (this outcome will be determined once before study start))
  • Change of questionnaire scores - muscular fatigue(30 days (questionnaires will be given to participants several times before, during, and after the intervention.))
  • Change of creatine kinase(30 days (blood is drawn from participants several times before, during, and after the intervention.))
  • Change of cytokines(30 days (blood is drawn from participants several times before, during, and after the intervention.))
  • Change of fat mass(10 to 21 days (assessment is conducted once before the intervention and repeated three times afterwards, i.e. 3, 7 and 14 days after the completion of the intervention))
  • Correlations between sleep quality devices(30 days)
  • Change of executive functions - Eriksen flanker task(30 days (executive functions are tested several times before, during, and after the intervention))

Investigators

Sponsor
University of Salzburg
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Nils Haller, PhD

Senior Researcher

University of Salzburg

Study Sites (1)

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