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Clinical Trials/NCT05213130
NCT05213130CompletedNot Applicable

The Relationship Between Blood Donation and Subjective Well-being

Guangzhou Blood Center1 site in 1 country601 target enrollmentStarted: January 18, 2022Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
601
Locations
1
Primary Endpoint
Score of Subjective Well-Being at Time 2

Study Overview

Brief Summary

This study investigates the psychological effects of blood donation among adult donors at the Guangzhou Blood Center. The primary objective is to examine whether a brief gratitude-based intervention delivered after donation enhances donors' subjective well-being (SWB) and basic psychological need (BPN) satisfaction. Participants who complete a whole-blood donation are randomly assigned to either an Intervention group, receiving a standardized gratitude reinforcement message accompanied by a vignette emphasizing the life-saving impact of donation, or a Control group that receives no additional message. All participants complete questionnaires at Time 1 (immediately after donation) and at Time 2 (4-22 days later), assessing SWB and related psychosocial variables.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Other
Masking
Single (Participant)

Eligibility Criteria

Ages
18 Years to 60 Years (Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Successfully completed a whole-blood donation at the Guangzhou Blood Center during the study period.
  • Able to read and understand the study materials and provide informed consent.
  • Provided the correct answer to a control question in the questionnaire
  • Provided their phone number.
  • Donated blood was successfully supplied to the hospitals.

Exclusion Criteria

  • Whole blood donors with positive or suspicious serological results.

Arms & Interventions

Gratitude-based intervention

Experimental

Participants in this group receive a standardized gratitude-based intervention immediately after completing whole-blood donation. The intervention consists of (1) a written gratitude reinforcement message acknowledging the donor's contribution and emphasizing the life-saving impact of their donation, and (2) a brief vignette illustrating how donated blood benefits patients in need. The purpose of this intervention is to enhance donors' subjective well-being and psychological need satisfaction by reinforcing their sense of autonomy, competence, and relatedness. Participants complete questionnaires at Time 1 (post-donation) and Time 2 (4-22 days later).

Intervention: Information (Other)

No Message

No Intervention

Participants in this group complete the standard post-donation procedure and receive no additional message or vignette. They complete the same questionnaires at Time 1 (post-donation) and Time 2 (4-22 days later) as the Intervention group. This arm serves as the comparison condition for evaluating the effect of the gratitude-based intervention on subjective well-being and related psychosocial outcomes.

Outcomes

Primary Outcomes

Score of Subjective Well-Being at Time 2

Time Frame: 4-22 days after donation

Subjective well-being (SWB) is assessed at follow-up using a validated multi-item measure capturing life satisfaction and affective well-being. Affect-Adjective Scale (validated Chinese version): 9 items, each scored 1-7. Satisfaction with Life Scale (validated Chinese version): 5 items scored 1-7. An aggregate SWB score was calculated by standardizing and summing life satisfaction scores with positive affect scores and subtracting the negative affect score from them. Scores range from low to high levels of well-being. The primary objective is to evaluate whether exposure to the gratitude-based intervention leads to higher SWB relative to the control condition.

Secondary Outcomes

  • Score of Basic Psychological Needs Satisfaction at Time 2(4-22 days after donation)
  • Score of Basic Psychological Needs Satisfaction at Time 1(Immediately after donation)
  • Score of Subjective Well-being at Time 1(Immediately after donation)
  • Score of Blood Donation Intention at Time 1(Immediately after donation)
  • Score of Blood Donation Intention Score at Time 2(4-22 days after donation)
  • Re-Donation Rate within One Year(Up to 12 months after the initial donation)

Investigators

Sponsor
Guangzhou Blood Center
Sponsor Class
Other Gov
Responsible Party
Principal Investigator
Principal Investigator

OUYANG Jian

Senior Investigator

Guangzhou Blood Center

Study Sites (1)

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