Management of childhood empyema: is there any abnormal lung-function after surgical intervention?
Completed
- Conditions
- All the people, who have had an childhood empyema since 1985, will be included. The patients must have been admitted in the VU hospital or AMC hospital, which are both in Amsterdam, and they must have had a surgical operation, such as video assisted thoracoscopic surgery, decortication or thoracotomy. At the moment of follow up they have to be 6 years or older.
- Registration Number
- NL-OMON25528
- Lead Sponsor
- VU medical centre (Amsterdam); see scientific contact
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1. The childhood empyemas treated by surgery must suffice the next criteria: 'febrile illness with pulmonary dysfunction', 'accumulation of fluid in the pleural space on X-thorax or ultrasound' and 'purulent fluid in pleural space or signs of loculations on X-thorax or ultrasound/ WBC count > 15.000/microl;
2. Patients have undergone video assited thorocoscopic surgery, decortication or thoracotomy.
Exclusion Criteria
1. Phase 1 empyemas;
2. Empyemas caused by trauma, surgery (other than interventional surgery) or tbc;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary study parameters of the pulmonary function test:<br /><br>1. Total lung capacity (TLC);<br /><br>2. FEV1/VC;<br /><br><br /><br /><br>Primary study parameter of the exersize test:<br /><br>3. VO2 max.
- Secondary Outcome Measures
Name Time Method Secundary study parameters of the pulmonary function test:<br /><br>1. Forced vital capacity (FVC);<br /><br>2. FEV1;<br /><br>3. Maximal mid-expiratory flow (MMEF25-75%);<br /><br>4. Residual volume (RV);<br /><br>5. Diffusion capacity.<br /><br><br /><br /><br>Secundary study parameters of the exersize test:<br /><br>6. Heart frequenty max. (HF max.);<br /><br>7. Max. exercise ventilation/max. voluntary ventilation;<br /><br>8. Max. tidal volume/inspiratorycapacity (Vt max/IC);<br /><br>9. O2 pulse;<br /><br>10. SO2;<br /><br>11. Respiratory quotiënt (VCO2/VO2).