A multi-centre randomised controlled trial comparing rubber band ligation with haemorrhoidal artery ligation in the management of symptomatic second and third degree haemorrhoids

Sheffield Teaching Hospitals NHS Foundation Trust (UK)0 个研究点目标入组 350 人开始时间: 2012年5月10日最近更新: 2019年12月10日

适应症

试验速览

•Current inclusion criteria as of 30/04/2013:
•1. Adults aged 18 years or over with symptomatic second or third degree haemorrhoids.
•Previous inclusion criteria until 30/04/2013:
•1. Adults aged 18 years or over with symptomatic second or third degree haemorrhoids
•2. Either presenting for the first time or after failure of RBL

•Current exclusion criteria as of 30/04/2013:
•1. Patients that have had previous surgery for haemorrhoids (at any time)
•2. Patients that have had more than one injection treatment for haemorrhoids in the past 3 years
•3. Patients that have had more than one RBL procedure in the past 3 years
•4. Patients with known perianal sepsis, inflammatory bowel disease, colorectal malignancy, pre-existing sphincter injury
•5. Patients with an immunodeficiency
•6. Patients that are unable to have general or spinal anaesthetic
•7. Patients currently taking Warfarin Clopidogrel or have any other hypocoagulability condition
•8. Patients currently taking Nicorandil
•9. Pregnant women
•10. Patients that are unable to give full informed consent (this may be due to mental capacity or language barriers)
•11. Patients previously randomised to this trial
•Previous exclusion criteria until 30/04/2013:
•1. Patients with known perianal sepsis, inflammatory bowel disease, colorectal malignancy, pre-existing sphincter injury
•2. Patients with an immunodeficiency
•3. Patients that are unable to have general or spinal anaesthetic
•4. Patients currently taking warfarin, or clopidogrel
•5. Patients currently taking Nicorandil
•6. Pregnant women
•7. Patients that are unable to give full informed consent (this may be due to mental capacity or language barriers)
•8. Patients previously randomised to this trial

发起方

Sheffield Teaching Hospitals NHS Foundation Trust (UK)