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Characterizing mechanisms of sensitivity and resistance to anti-androgen therapy with whole-body molecular imaging.

Recruiting
Conditions
metastatic castration-resistant prostate cancer
Registration Number
NL-OMON26005
Lead Sponsor
Amsterdam UMC, location VUmc
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
50
Inclusion Criteria

1. Histologically confirmed prostate cancer adenocarcinoma
2. Eligible for abiraterone treatment as judged by the treating physician.
3. Castrate levels of serum testosterone
4. Progressive disease manifest by either imaging (bone imaging, MRI, CT, or PSMA PET-CT) or biochemical progression (PSA).
5. Visible lesions on CT, bone imaging, MRI, or PSMA PET-CT consistent with disease.

Exclusion Criteria

1. Previous anaphylactic reaction to either FDHT or PSMA.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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