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临床试验/NCT04469647
NCT04469647Unknown不适用

COVID 19 Antibody Seroprevalence Amongst Healthcare Workers in Johns Hopkins Aramco Healthcare

Johns Hopkins Aramco Healthcare1 个研究点 分布在 1 个国家目标入组 1,200 人开始时间: 2020年7月19日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
1,200
试验地点
1
主要终点
Seroconversion status

研究概览

简要总结

Healthcare workers play a critical role in fighting the pandemic, not only by managing the patients' health clinically, but also by implementing adequate measures for infection prevention and control in healthcare facilities. This puts healthcare workers at a greater risk of acquiring the disease. COVID-19 is caused by Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2) and many people can be infected with it asymptomatically and undetectably.

Serology is an antibody test that provides additional information to polymerase chain-reaction (PCR) testing as it is the only way to reliably establish the fraction of the population that was infected . Seroconversion is the development of antibodies in the blood which can confirm suspected cases after the fact and reveal who was infected but asymptomatic and never realized it. Antibodies are specific proteins created as the body's response to the infection and this test is essential for detecting infected individuals with few or no symptoms at all.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • JHAH employee
  • Housekeepers (this group of staff are outsourced at JHAH)

排除标准

  • Any participant exhibiting COVID 19 symptoms

结局指标

主要结局

Seroconversion status

时间窗: 6 Months

Percentage of health care workers with positive serological markers to describe patterns in exposure, re-infection, clinical symptom, serological responses among health care workers based on their baseline serological status over a one year period.

次要结局

  • Identification of risk factors for COVID 19 seroconversion in asymptomatic healthcare workers(6 Months)
  • The durability of COVID 19 seroconversion in asymptomatic healthcare workers at JHAH(6 Months)
  • The proportion of asymptomatic infections among staff who have seroconverted(6 Months)

研究者

发起方
Johns Hopkins Aramco Healthcare
申办方类型
Other
责任方
Sponsor

研究点 (1)

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