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Clinical Trials/NCT06221449
NCT06221449
Completed
Not Applicable

Effect of Lung Recruitment on Atelectasis in Lung-Healthy Patients Undergoing Laparoscopic Cholecystectomy

Menoufia University1 site in 1 country93 target enrollmentFebruary 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Atelectasis, Postoperative
Sponsor
Menoufia University
Enrollment
93
Locations
1
Primary Endpoint
Incidence of atelectasis
Status
Completed
Last Updated
last year

Overview

Brief Summary

The goal of this clinical trial study is to assess the effectiveness of different methods of lung recruitment maneuver on the incidence of atelectasis in adults undergoing laparoscopic cholecystectomy surgery using lung ultrasound Participants will be divided into three groups as: Control group, sustained inflation group (SI) and Stepwise Positive end expiratory pressure increasing group(Third group). Each contains 31 patients.

Control Group = Keep parameters all through the procedure without any changing GROUP(SI) = After abdominal deflation, we will apply sustained inflation by adjusting Adjustible pressure Limiting valve 40 centimetres water on spontaneous mode, holding the bag for 30 second.

Third group = After abdominal deflation, we will apply stepwise Positive Pressure increasing by 2 centimetres water every 5 breathing cycles till reaching 12 centimetres water and keeping it till extubation, with a maximum airway pressure not exceeding 40 centimetres water.

Detailed Description

the effectiveness of different methods of lung recruitment maneuver on the incidence of atelectasis in adults undergoing laparoscopic cholecystectomy surgery using lung ultrasound Participants will be divided into three groups as: Control group, sustained inflation group (SI) and Stepwise POSITIVE pressure increasing group. Each contains 31 patients. Control Group = Keep parameters all through the procedure without any changing GROUP(SI) = After abdominal deflation, The investigators will apply sustained inflation by adjusting Adjustible pressure valve 40 centimetres water spontaneous mode, holding the bag for 30 second. Third group = After abdominal deflation, the investigators will apply stepwise POSITIVE pressure increasing by 2 centimeters water 5 breathing cycles till reaching 12 centimetres water and keeping it till extubation, with a maximum airway pressure not exceeding 40 centimetreswater. During the entire procedure the transducer head will be placed over one point of the chest selected by the operator where the area of atelectasis was detected The probe will be placed in the atelectasis area.

Registry
clinicaltrials.gov
Start Date
February 1, 2024
End Date
May 15, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Amany Said Abdel Haleem

Lecturer

Menoufia University

Eligibility Criteria

Inclusion Criteria

  • Patients with healthy lungs
  • Age between 18 and 65 years old
  • Body mass index (BMI) \<30 kg / m2
  • Physical status I-II of the American Society of Anesthesiologists (ASA)
  • Elective laparoscopic cholecystectomy.

Exclusion Criteria

  • Patient refusal
  • Patients with preoperative ultrasound evidence of pulmonary atelectasis.
  • Patients who will have conversion from laparoscopic to open surgery.
  • Patients experiencing critical postoperative complications such as severe subcutaneous emphysema and pneumothorax.
  • Patients with pulmonary, cardiac, and neuromuscular diseases and a corresponding surgical history and respiratory tract infections.

Outcomes

Primary Outcomes

Incidence of atelectasis

Time Frame: one hour

incidence

Secondary Outcomes

  • Heart rate(Two hour)
  • Lung ultrasound score(one day)
  • Blood pressure ( millimetre Mercury)(Two hour)
  • Hospital length of stay(One day)

Study Sites (1)

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