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How safe and effective is drugs like enoxaparin and apixaban is for preventing clot formation in your blood vessel after you undergo total hip or total knee replacement surgeries?

Not Applicable
Registration Number
CTRI/2018/11/016428
Lead Sponsor
AIIMS JODHPUR
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Signed written informed consent

1) Subjects giving informed consent.

Target population

2) Subjects undergoing either elective unilateral or same-day bilateral total knee

arthroplasty and total hip arthroplasty.

3) Subject willing to undergo bilateral Doppler studies.

Exclusion Criteria

1.Hereditary (first degree) or acquired bleeding or coagulation disorder.

2.Known or suspected history of heparin-induced thrombocytopenia.

3.Need for ongoing treatment with a parenteral or oral anticoagulant (eg,

Subjects with mechanical valves, warfarin-eligible atrial fibrillation).

4.Known coagulopathy.

5.Active bleeding or at high risk for bleeding.

6.Active hepatobiliary disease.

7.Any condition, in the opinion of the investigator, for which surgery or administration of an anticoagulant was contraindicated.

8.Hypersensitivity to unfractionated heparin, low molecular weight heparin, porcine products, or iodinated contrast medium.

9.Pre-operative Deep Vein Thrombosis Detected in Doppler USG and patients with previous known / documented history of thrombogenic events like DVT and pulmonary embolism

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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