SAFETY AND EFFICACY OF APIXABAN AND ENOXAPARIN IN PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY AND TOTAL KNEE ARTHROPLASTY: A PROSPECTIVE OBSERVATIONAL STUDY

AIIMS JODHPUR0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Signed written informed consent
•1) Subjects giving informed consent.
•Target population
•2) Subjects undergoing either elective unilateral or same-day bilateral total knee
•arthroplasty and total hip arthroplasty.
•3) Subject willing to undergo bilateral Doppler studies.

•1.Hereditary (first degree) or acquired bleeding or coagulation disorder.
•2.Known or suspected history of heparin-induced thrombocytopenia.
•3.Need for ongoing treatment with a parenteral or oral anticoagulant (eg,
•Subjects with mechanical valves, warfarin-eligible atrial fibrillation).
•4.Known coagulopathy.
•5.Active bleeding or at high risk for bleeding.
•6.Active hepatobiliary disease.
•7.Any condition, in the opinion of the investigator, for which surgery or administration of an anticoagulant was contraindicated.
•8.Hypersensitivity to unfractionated heparin, low molecular weight heparin, porcine products, or iodinated contrast medium.
•9.Pre-operative Deep Vein Thrombosis Detected in Doppler USG and patients with previous known / documented history of thrombogenic events like DVT and pulmonary embolism

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