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临床试验/CTRI/2025/08/092944
CTRI/2025/08/092944尚未招募不适用

Assessment of efficacy of Dhatri Pindi in Pittaj Abhishyanda:Randomised Controlled Trial

PMTs Ayurveda College1 个研究点 分布在 1 个国家目标入组 72 人开始时间: 2025年8月29日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
72
试验地点
1
主要终点
To evaluate efficacy of Dhatri Pindi Kalpna in Pittaj Abhishyanda.

研究概览

简要总结

Abhishyanda is considered as Sarvagata Netraroga which is a dreadful disease and possess symptoms of conjunctivitis as per the modern science. The inflammation of conjunctiva mainly occurs in Abhishyanda which can spread through Rakta. Abhishyanda if not cured then it can causes Adhimanth associated with acute pain. The other complication may include, Sandhigat roga shuklagat roga, Krishnagat roga and Vartmagat roga, etc. Abhishyanda is put as disease amongst the seventeen Sarvagat rogas. Ayurveda classics mentioned various types of Abhishyanda including Vataja Abhishyanda, Pittaja Abhishyanda, Kaphaja Abhishyanda and Raktaja Abhishyanda. The disease involves Kledana in Doshas and Dhatu due to which profuse discharge comes out from the eye. Therefore excessive discharge from eye is the major feature of Abhishyanda. Ayurveda described different approaches such as Anjana, Pariseka, Pralepa, Aschyotana, Tarpana, Sweda ,Pindi ,Bidalak , and Putpaka for the management of various Netraroga. Some ayurveda formulations and herbs also offers relieves in the symptoms of Abhishyanda,In view of the magnitude of the problem, the discomfort it causes to the patients and the cost of the treatment, there is need to develop a therapy which is free from side effects, cheaper, and has a significant effect in alleviating the symptoms of the patients. As above mentioned kalpanas the Pindi Kalpna is the topic which remained untouched.there is no significant work done on Pindi Kalpna in today’s era hence ,This study is an attempt in this direction to evaluate the effects of Dhatri Pindi on mucopurulent conjunctivitis. However amongest the topical remedies the most simple,practical yet effective procedures giving better results in local inflammations and painful condition of the eye thereby giving an instant and immediate effect is Pindi kalpna,For Dhatri Phalam- The literary study of fruit Amalaki from Ayurvedic texts and modern researches concludes that fruit that is Embelica officinalis has following properties according to Ayurveda, Rasayana, Vrushya, Chakshushya, Panduhar, Krimihar, Udarhar, Vaysthapana, Pramehhar, Kamalahar, and according to modern Antioxidant, Anti-inflammatory,Antimicrobial,Analgesic, Anticancer, Hepatoprotective, Gastroprotective, Anticarcinogenic.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • The patients presenting with signs and symptoms of Pittaj Abhishyanda (Netra lalima, Kleda, Daah etc.).
  • Patients willing to give informed & written consent.
  • Irrespective of sex and Socioeconomics status.

排除标准

  • Patients suffering from trachoma, dacrocystitis etc.
  • Patients with known case of HIV/Hbsag
  • Patients not willing for trial.

结局指标

主要结局

To evaluate efficacy of Dhatri Pindi Kalpna in Pittaj Abhishyanda.

时间窗: 7 day treatment with 4 follo up 0,3,5 and 7th day

次要结局

  • To review data related to Pittaj Abhishyanda and Pindi Kalpna in Ayurvedic texts.(To review data related to Bacterial Conjunctivitis in Modern texts.)

研究者

发起方
PMTs Ayurveda College
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Dr Nikita Milind Rohokale

PMTs Ayurveda College,Shevgaon

研究点 (1)

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