Labor Analgesia in the Latent Phrase

Not Applicable

Completed

• Conditions: Labor Pain
• Interventions: Procedure: Active phrase epidural analgesia; Procedure: Latent phrase epidural analgesia

• Registration Number: NCT00647725
• Lead Sponsor: Nanjing Medical University

Brief Summary

Painless labor is an essential part in woman's health care. Labor analgesia in the active phrase is in popular use currently. However, parturients are still haunted by the labor delivery pain in the latent phrase up to 7-8 hours, especially for the nulliparas. Therefore, we hypothesized that labor analgesia in the latent phrase of the first delivery stage would provide superior health care for laboring women. In addition, such analgesia technique would not prolong the time of uterine dilation and labor delivering.

Detailed Description

Not available

Study Timeline

• Study Start: 2003-01
• Primary Completion: 2007-12
• Study Completion: 2007-12
• Study First Submitted: 2008-03-28
• Study First Submitted QC: 2008-03-31
• Study First Posted: 2008-04-01
• Status Verified: 2009-09
• Last Update Submitted: 2009-09-30
• Last Update Posted: 2009-10-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 15000

Inclusion Criteria

• Nulliparas
• Required labor analgesia
• Chinese.

Exclusion Criteria

• Allergic to opioids and/or local anesthetics
• Failed to performing epidural catheterization
• Organic dysfunction
• Contraindications for epidural analgesia.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
I	Active phrase epidural analgesia	Active phrase analgesia
II	Latent phrase epidural analgesia	Latent phrase analgesia

Primary Outcome Measures

Name	Time	Method
Rate of Cesarean delivery	The time of the end of the labor

Secondary Outcome Measures

Name	Time	Method
Oxytocin infusion rate	During the whole period of laboring
Time of latent phrase	From the beginning of regular contraction of uterus to the diameter of cervix to 4cm
Time of labor	From the beginning of regular contraction of uterus to the end of the labor
Overall feeling of satisfaction of analgesia	From the beginning of regular contraction of uterus to the end of the labor
Side effects	From the beginning of regular contraction of uterus to the end of the labor
VAS pain intensity	From the intinition of analgesia to the cervical dilation >4cm
Instrumental delivery	The end of the time of the labor
Neonatal Apgar scores	1st min, 5th min, 10th min and 20th min
Umbilical gas measurement	After delivering of the fetus
Maternal oral temperature	From the initiation of analgesia to the end of the labor
Maternal corticosteroids	1h before analgesia; 0h of the analgesia; 5min,10min,30min,45min,1h,2h,3h and hourly till the end of the labor

Trial Locations

Locations (1)

Nanjing Maternal and Child Health Care Hospital; 🇨🇳 Nanjing, Jiangsu, China