Predictive Value of Triglyceride-Glucose index for Disease Severity and Mortality in Icu patients with Sepsis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 135
- 试验地点
- 1
- 主要终点
- Survived or non-survived (In-hospital mortality)
研究概览
简要总结
Baseline patient characteristics including demographic data (age, gender), presence of comorbidities, ICU admission diagnosis, source of infection, vital signs, duration of intensive care unit (ICU) stay, need for mechanical ventilation, will be noted using a predefined format.Vital signs, scoring system results, and laboratory parameters will be recorded within the first 24 hours following admission to the ICU.Disease Severity Scores such as Sequential Organ Failure Assessment (SOFA) Score, and Acute Physiology and Chronic Health Evaluation (APACHE-II) Score will be noted at ICUadmission.Routine laboratory findings, including complete blood count, kidney function tests, liver function tests, serum electrolytes, coagulation parameters, and arterial blood gas analysis, performed within 24 hours of ICU admission will be recorded.Metabolic markers such as triglycerides (mg/dL), fasting glucose (mg/dL), and the TyG index within the same timeframe will observed and will be noted.All patients admitted to the hospital with sepsis will be followed up for the clinical outcome. Only one admission of the patient during the study period will be considered.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)(—)
- 性别
- All
入选标准
- •Adult patients more 18 year old admitted to the intensive care unit with diagnosis of sepsis, defined according to sepsis -3 criteria(suspected or confirmed infection with sofa sequential organ failure assessment (SOFA)score of more than3).
排除标准
- •patient with missing triglyceride or glucose values within 24 hours of ICU admission.icu stay within 24 hours(early discharge,or death within one day) patient with decompensated liver disease or end stage kidney disease requiring dialysis,patient receiving lipid lowering drugs, and pregnant patients.
结局指标
主要结局
Survived or non-survived (In-hospital mortality)
时间窗: 7 days
次要结局
- 1)Duration of hospitalization in days(2)Need for mechanical ventilation)
研究者
Akshat Mehrotra
Kasturba hospital manipal
