Combined Effects of Turmeric Supplementation and Strengthening Exercises on Knee Pain, Physical Function and Quality of Life among Knee Osteoarthritis Patients.

Phase 2

Completed

• Conditions: knee osteoarthiritis; Knee Osteoarthritides; Osteoarthritis of the Knee; Knee Osteoarthritis; Osteoarthritis of Knee

• Registration Number: TCTR20230615003
• Lead Sponsor: self funding

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2023-06-02
• Study Start: 2023-06-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

Male and female patients who sought physiotherapy treatment at Hospital Universiti Sains Malaysia
Age between 35-80 years old
Symptomatic Knee OA
Bilateral or single knee OA
Kellgren-Lawrence grades of II or III upon radiographic classification
Active full range of knee movement
BMI 18.5-29.9 kg/m2

Exclusion Criteria

Allergy to turmeric supplements or herbal medication
Candidate for surgical procedure
Secondary OA due to trauma, rheumatoid arthritis, hemophilia and surgery.
Intra-articular steroid injection done within the 3 months period.
Using corticosteroids
Presents with heart, liver and renal failure
BMI > 30kg/m2
Smoker

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual Analogue Scale (VAS) pretest, mid-test(6th week) and post test (12th week) pain scale,Quality of life questionnaires-Malay version (WHOQOL-BREF) pretest, mid-test(6th week) and post test (12th week) Quality of life

Secondary Outcome Measures

Name	Time	Method
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pretest, mid-test(6th week) and post test (12th week) are pain (5 items), stiffness (2 items), and physical function (17 items).,6-minute walking test (6MWT) pretest, mid-test(6th week) and post test (12th week) distance walked by patients