A Prospective randomized control trial to compare the analgesic effect of epidural Dexmedetomidine plus Bupivacaine and epidural Ketamine plus Bupivacaine in patients with hip factures

Ganga Hospital1 个研究点分布在 1 个国家目标入组 60 人开始时间: 2012年1月9日最近更新: 2014年6月26日

试验速览

阶段: 不适用
状态: 已完成
发起方: Ganga Hospital
入组人数: 60
试验地点: 1
主要终点: VAS score less than 3 at operative site

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

A prospective randomized double blind controlled trial including 60 ASA I & II patients between age 18 â€“ 75 yrs for elective hip fracture surgery divided into 2 groups Group K Ketamine plus Bupivacaine and Group D Dexmedetomidine plus Bupivacaine. The study compares the effects of dexmedetomidine plus bupivacaine and preservative free ketamine plus bupivacaine in hip fracture surgeries in postoperative period for 48 hrs with continuous epidural infusion and thus concluding which drug combination produces better analgesia with minimal haemodynamic alterations.

研究设计

研究类型: Interventional
分配方式: Computer generated randomization
盲法: Participant, Investigator and Outcome Assessor Blinded

入排标准

年龄范围: 18.00 Year(s) 至 75.00 Year(s)（—）
性别: All

入选标准

•American Society Anaesthesia (ASA) physical status I and II patients, Both sex, Hip fracture surgeries, Elective Surgeries.

排除标准

•Allergy to the drug being used, Refusal of patient to regional anaesthesia,Bleeding diasthesis, With uncontrolled hypertension, Heart rate <60 beats/minute.

结局指标

主要结局

VAS score less than 3 at operative site

时间窗: 48 hours

次要结局

Motor blockade Swnsory blockade(Side effects)

研究者

发起方

Ganga Hospital

申办方类型

Research institution and hospital

研究点 (1)

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