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Effects of tadalafil on postvoided dribbling

Not Applicable
Completed
Conditions
Diseases of The genitoruinary system
Registration Number
KCT0002232
Lead Sponsor
Hallym University Medical Center- Chuncheon
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Male
Target Recruitment
102
Inclusion Criteria

1. 20 = age < 70
2. intenational prostate symptome score >8
3. Hallym post voided dribbling questionnaire >1
4. He must have a sexual partner and have a sexual relationship more than two per a month
5. He voluntarily participated in this study

Exclusion Criteria

(1) stroke, myocardial infarction,Coronary artery bypass graft surgery history with in 6 months
(2) cardiac failure, unstable angina, life-threatening arrhythmia with in 6 months
(3) uncontrolled Diabetes mellitus (HbA1C > 12%)
(4) proliferative diabetic retinopathy
(5) Spinal injury, pelvic surgery history
(6) lower blood pressure thant 90/50mmHg, higher blood pressure more than170/100mmHg
(7) penile curvature, urethral stricture, Pyeronie's disease
(8) abnormal liver or renal function
(9)retinitis pigmentosa
(10) active peptic ulceration within 1 year
(11) Obvious candidate of Priapism (leukemia..)
(12) congenital QT prolongation syndrome patinet, drug medication with prolonged QT interval
(13) psychotic disorder
(14) Nitrates/Nitric oxide(NO) donor(ex. nitroglycerin, isosorbide mononitrate, isosorbide dinitrate, amyl nitrate/nitrite, Sodium nitroprusside)
(15)cancer chemotherapy
(16) anticoagulants medication
(17) affect for metabolism CYP3A4
(18) other phosphodiesterase-5 (PDE5) inhibitor medication within 2 weeks
(19) other Randomized Clinical Trial participants
(20) hypersensitivity history associated with phosphodiesterase-5 (PDE5) inhibitor

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Quantitative Evaluation of Post-Voided Dribbling using paper towel ;Scores of Post Voided Dribbling Questionnaire
Secondary Outcome Measures
NameTimeMethod
Scores of International Index of Erectile Function 15
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