EUCTR2019-002232-82-SE进行中（未招募）1 期
Downstream targets of SSRI effect in treatment of Major Depressive Disorder
适应症
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •age 20-80 years
- •ongoing major depressive episode according to M.I.N.I. interview
- •healthy, apart from MDD, according to MRI, clinical interview, physical examination, blood tests (Hb, ASAT, ALAT, GT, Na, K, creatinine, calcium, albumin, TSH, glucose).
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 15
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 5
排除标准
- •ongoing pharmacological treatment (wash out-time one month, drugs not used for MDD treatment and without serotonergic effect may be allowed at the discretion of the PI)
- •bipolar disorder
- •psychotic syndrome
- •alcohol/drug dependence
- •organic central nervous system disorder
- •patient who is not suitable for MRI (claustrophobia, MRI incompatible metal implants)
- •pregnancy.
- •Allergy or hypersensitivity to escitalopram
- •Ongoing treatment with any medication that is known to prolong the QT interval
- •Ongoing treatment with any monoamine oxidase inhibitor
研究者
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