Treament for Colorectal Neoplasms by Metod Endoscopic Mucosal Resection With Circumferential Mucosal Incision
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Endoscopic Mucosal Resection With Circumferential Incision
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- R0 resection rate
- Status
- Active, not recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
This is a prospective randomized trial to improve the results of treatment of patients with colorectal neoplasms.
Detailed Description
Generally, endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are the methods of choice for the removal of benign and early malignant neoplasms of the colon. However, there are certain difficulties in terms of the EMR technique - this is an increase in the frequency of fragmentation with a lesion size of more than 20 mm, which in turn increases the risk of recurrence; with regard to ESD technique, this is a long procedure time; high incidence of complications; significant time required for teaching the technique; technical difficulties. In this regard, it is worth paying attention to the method of "endoscopic mucosal resection with circumferential mucosal incision" (C-EMR). This method deserves interest due to the fact that it allows more often to perform en-block resections in comparison with the classical method of endoscopic mucosal resection (EMR - endoscopic mucosal resection); technically easier to do; takes a short procedure time.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients with benign colon neoplasms without signs of deep invasion (I, II, IIIL and IV type according to Kudo, I and II type according to Sano)
- •the size of the neoplasm is from 20 mm to 30 mm
- •patient for treatment
Exclusion Criteria
- •unsatisfactory tumor lifting
- •refusal of the patient from research at any stage of treatment
Outcomes
Primary Outcomes
R0 resection rate
Time Frame: 14 day
Secondary Outcomes
- intervention time(1 day)
- conversion rate(1 day)
- En-block resesction rate(14 day)
- intra- and postoperative complications rate(30 day)