Clinical application of embryonic membrane in middle ear surgery

Not Applicable

• Conditions: choronic otitis media with choleasteaoma.; Chronic atticoantral suppurative otitis media, Other chronic suppurative otitis media,Suppurative otitis media, unspecified,Chronic mastoiditis; H66.2,H66.

• Registration Number: IRCT2015081915496N16
• Lead Sponsor: Vice Chancellor of Research, Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

all patients more than 18 years old; canal wall down mastoidectomy because of choronic otitis media with choleastetoma; final size of tympanic membrane perforation more than 50%.

Exclusion criteria: revision surgery; pre operative medical problems such as asthma, diabetes, coagulation disorders, cardiovascular disease, basic metabolic disorder and chronic liver or renal disease; patients without adequate follow up (less than 6 months); canal wall down mastoidectomy because of other reason such as tumors.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tympanic membrane graft successes rate. Timepoint: within 6 months after surgery. Method of measurement: Observation by physician.;Epithelialization. Timepoint: within 6 months after surgery. Method of measurement: Observation by physician.;Otorrhea. Timepoint: within 6 months after surgery. Method of measurement: Observation by physician.;Existance granulation tissue. Timepoint: within 6 months after surgery. Method of measurement: Observation by physician.;Hearing threshold. Timepoint: before operation -6 months after operation. Method of measurement: pure tone audiometry.