A Clinical Study for Developing Artificial Intelligence(AI)-Based Clustering Model for Personalized Medicine in Acute Respiratory Failure

Recruiting

• Conditions: Acute Respiratory Failure

• Registration Number: NCT06479421
• Lead Sponsor: Samsung Medical Center

Brief Summary

We will prospectively collect clinical information to develop a clustering analysis model and confirm phenotype for patients with acute respiratory failure who admit to the intensive care unit and require oxygen supply beyond a high flow nasal cannula, and a control group without acute respiratory failure. and clinical characteristics and prognosis will be compared.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-14
• Status Verified: 2024-06
• Study First Submitted: 2024-06-24
• Study First Submitted QC: 2024-06-24
• Last Update Submitted: 2024-06-24
• Study First Posted: 2024-06-28
• Last Update Posted: 2024-06-28
• Primary Completion: 2025-02-28
• Study Completion: 2025-02-28

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

• Acute Respiratory Failure group

Among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital, if all of the following conditions are met:

1. Age 18 or older 2) Patients who require treatment with high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) due to acute respiratory failure.

• control group For comparative analysis, among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital who meet all of the following conditions, they are registered as a control group with the consent of the subjects and undergo the same research procedure.

1. Age 18 or older

2. Patients who do not require high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) treatment

Exclusion Criteria

If any of the following criteria applies, you will not be permitted to participate in this clinical trial.

1. Patients 48 hours after oxygen treatment (HFNC, NIV (BIPAP or CPAP), MV)
2. Patients transferred from another hospital
3. Patients with limitations in treatment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hospital Mortality	From date of admission until the date of hospital discharge or date of death from any cause, whichever came first, assessed up to 1 year	clinical outcomes - Hospital Mortality

Secondary Outcome Measures

Name	Time	Method
ICU Mortality	From date of ICU admission until the date of ICU discharge or date of death from any cause, whichever came first, assessed up to 6 months	clinical outcomes - ICU Mortality
ICU length of stay	From date of ICU admission until the date of ICU discharge, assessed up to 6 months	clinical outcomes - ICU length of stay
Hospital length of stay	From date of hospital admission until the date of hospital discharge, assessed up to 1 years	clinical outcomes - Hospital length of stay

Trial Locations

Locations (1)

Samsung Medical Center; 🇰🇷 Seoul, Gangnam, Korea, Republic of