A Clinical Study for Developing AI-based Clustering Model for Personalized Medicine in Acute Respiratory Failure: Single Center, Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 250
- 试验地点
- 2
- 主要终点
- Hospital Mortality
研究概览
简要总结
The investigators will prospectively collect clinical information to develop a clustering analysis model and confirm phenotype for patients with acute respiratory failure who admit to the intensive care unit and require oxygen supply beyond a high flow nasal cannula, and a control group without acute respiratory failure. and clinical characteristics and prognosis will be compared.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •# Inclusion Criteria:
- •- Acute Respiratory Failure group
- •Among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital, if all of the following conditions are met:
- •1) Age 18 or older 2) Patients who require treatment with high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) due to acute respiratory failure.
- •- control group For comparative analysis, among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital who meet all of the following conditions, they are registered as a control group with the consent of the subjects and undergo the same research procedure.
- •Age 18 or older
- •Patients who do not require high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) treatment
排除标准
- •If any of the following criteria applies, participants will not be permitted to participate in this clinical trial.
- •Patients 48 hours after oxygen treatment (HFNC, NIV (BIPAP or CPAP), MV)
- •Patients transferred from another hospital
- •Patients with limitations in treatment
研究组 & 干预措施
Acute Respiratory Failure group
Among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital, if all of the following conditions are met:
- Age 18 or older
- Patients who require treatment with high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) due to acute respiratory failure.
Control group
For comparative analysis, among patients admitted to the internal medicine intensive care unit at Samsung Seoul Hospital who meet all of the following conditions, they are registered as a control group with the consent of the subjects and undergo the same research procedure.
- Age 18 or older
- Patients who do not require high flow nasal cannula (HFNC), non-invasive ventilation (NIV (BIPAP or CPAP)), or mechanical ventilation (MV) treatment
结局指标
主要结局
Hospital Mortality
时间窗: From date of admission until the date of hospital discharge or date of death from any cause, whichever came first, assessed up to 1 year
clinical outcomes - Hospital Mortality
次要结局
- ICU Mortality(From date of ICU admission until the date of ICU discharge or date of death from any cause, whichever came first, assessed up to 6 months)
- ICU length of stay(From date of ICU admission until the date of ICU discharge, assessed up to 6 months)
- Hospital length of stay(From date of hospital admission until the date of hospital discharge, assessed up to 1 years)
研究者
Ryoung-Eun Ko
Clinical assistant professor
Samsung Medical Center