Evaluation of Capers fruits effects on diabetic neuropathy

Phase 2

Completed

Conditions: Diabetic Neuropathy.
Diabetic polyneuropathy
G63.2*

Registration Number: IRCT2016102630524N1

Lead Sponsor: Vice Chancellor for Research of Mashhad University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 70

Inclusion Criteria

age 18 to 65 years, diabetes mellitus type II, diabetic peripheral neuropathy.
Exclusion criteria: other types of neuropathy, pregnancy and lactation, foot ulcer or amputation, consumption of antidepressants, anticonvulsants or other analgesics.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The severity of neuropathy. Timepoint: Before and one month after intervention. Method of measurement: Michigan Neuropathy Screening Instrument (MNSI) And Neuropathy Total Symptom Score -6 (NTSS-6).;Neuropathic pain. Timepoint: Before and one month after intervention. Method of measurement: Visual Analog Scale for Pain.;Paresthesia. Timepoint: Before and one month after intervention. Method of measurement: Visual Analog Scale.

Secondary Outcome Measures

Name	Time	Method
Fasting blood sugar. Timepoint: Before and one month after intervention. Method of measurement: Glucose oxidase method.;Blood lipids (triglyceride and cholesterol). Timepoint: Before and one month after intervention. Method of measurement: Blood biochemical tests by using colorimetric method.;Renal Function Tests (Blood Urea Nitrogen (BUN), creatinine). Timepoint: Before and one month after intervention. Method of measurement: Blood biochemical tests by using colorimetric method.;Liver enzymes tests: Alanine transaminase (ALT), Aspartate transaminase (AST), Alkaline phosphatase (ALP). Timepoint: Before and one month after intervention. Method of measurement: Blood biochemical tests by using colorimetric method.