Linezolid vs. Vancomycin/Oxacillin/Dicloxacillin in the Treatment of Catheter-Related Gram-Positive Bloodstream Infections

Pfizer0 个研究点目标入组 739 人开始时间: 2002年4月最近更新: 2009年9月14日

适应症

试验速览

阶段: 3 期
状态: 已完成
发起方: Pfizer
入组人数: 739
主要终点: The empiric treatment of patients with complicated skin and skin structure infections (cSSSI) related to an indwelling catheter;

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

This study will treat patients who have a short term central catheter that is thought to be infected with a specific bacteria (gram positive bacteria)

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: None

入排标准

年龄范围: 13 Years 至 —（Child, Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Patients with a central indwelling catheter with signs and symptoms of infection

排除标准

•Patients with tunneled catheter which cannot be removed.
•Patients with evidence of endovascular infection including endocarditis.
•Patients with infection of permanent intravascular devices.
•Patients who have received more than 1 day of another antibiotic before enrollment.
•Patients with HIV and low CD4 count.

结局指标

主要结局

The empiric treatment of patients with complicated skin and skin structure infections (cSSSI) related to an indwelling catheter;

The empiric treatment of patients with gram-positive catheter-related bloodstream infections.

次要结局

Clinical efficacy of linezolid compared to vancomycin/oxacillin/dicloxacillin.2.Incidence of late metastatic sequelae associated with S. aureus infections in patients treated with linezolid

研究者

发起方

Pfizer

申办方类型

Industry

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