Cardiac MRI in Ischemic Stroke Study
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 103
- Locations
- 2
- Primary Endpoint
- Sensitivity and specificity of contrast medium-enhanced cardiac magnetic resonance imaging to detect echocardiography-proven cardiac sources of embolism in patients with acute ischemic stroke.
Study Overview
Brief Summary
The purpose of this prospective single-center trial is to compare the safety and diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging and transesophageal echocardiography in patients with acute ischemic stroke.
Detailed Description
Primary safety objective: Contrast medium-enhanced cardiac magnetic resonance imaging is safe in patients with acute ischemic stroke. Primary outcome: The diagnostic value of contrast medium-enhanced cardiac magnetic resonance imaging is comparable to transesophageal echocardiography in patients with acute ischemic stroke.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with acute ischemic stroke detected by brain magnetic resonance imaging.
Exclusion Criteria
- •Known atrial fibrillation or cardiac source of embolism
- •Severe aphasia
- •Acute infection or chronic inflammation
- •Severe arteriosclerosis or stenosis of brain-supplying arteries
- •Contraindications for magnetic resonance imaging or transesophageal echocardiography.
Outcomes
Primary Outcomes
Sensitivity and specificity of contrast medium-enhanced cardiac magnetic resonance imaging to detect echocardiography-proven cardiac sources of embolism in patients with acute ischemic stroke.
Time Frame: < 1 week after ischemic stroke
Secondary Outcomes
- Rate of unrecognised myocardial infarction detected by late gadolinium-enhanced cardiac MRI in patients with acute ischemic stroke.(< 1 week after ischemic stroke)
Investigators
Karl Georg Haeusler
MD
Charite University, Berlin, Germany