DECRYPT: Delivery of cognitive therapy for young people after trauma

Phase 2

• Conditions: Post-traumatic stress disorder; Mental and Behavioural Disorders

• Registration Number: ISRCTN12077707
• Lead Sponsor: niversity of East Anglia

Brief Summary

2021 protocol in https://pubmed.ncbi.nlm.nih.gov/34210731/ (added 05/07/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-10-24
• Last Update Posted: 21 July 2021
• Study Completion: 2024-06-30

Recruitment & Eligibility

• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Children and adolescents aged 8-17 years
2. Experiencing high levels of PTSD symptoms (scoring 17 or above on the CRIES-8)
3. Diagnosis of PTSD (as defined by DSM-5) following multiple trauma exposure

Exclusion Criteria

1. Any change of prescribed psychiatric medication within the past two months
2. PTSD symptoms only related to a single traumatic event
3. Developmental/neurodevelopmental disorder (e.g. autism)
4. Diagnosis of intellectual disability
5. Primary psychiatric diagnosis that warrants treatment ahead of PTSD (e.g. psychosis, severe depression, suicidal behaviour)
6. Inability to speak and understand English
7. On-going threat (e.g. living with an abuser) or safeguarding issue
8. Strong likelihood of being unable to complete treatment (e.g. imminent house move or placement move)
or
9. History of organic brain damage

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
evels of symptoms of PTSD are measured using the Child Revised Impact of Event Scale (CRIES-8) completed at baseline and at 2.5, 5 and 11 months post-randomisation.