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Confocal laser endomicroscopy in patients with non-resolving acute respiratory failure

Recruiting
Conditions
ARDS, COVID19
Registration Number
NL-OMON25385
Lead Sponsor
Amsterdam UMC
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
15
Inclusion Criteria

=18 years of age
- Non-resolving acute respiratory failure mandating a standard diagnostic bronchoscopy with bronchoalveolar lavage

Exclusion Criteria

- Inability and willingness to provide informed consent by family-members
- Patients on extra corporal membrane oxygenation (ECMO)

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Identification of specific CLE patterns of the alveolar compartment in invasively ventilated COVID 19 patients
Secondary Outcome Measures
NameTimeMethod
Description of how CLE patterns change over time within the same patients, Descriptive correlation of CLE patterns with Chest CT, lung ultrasound, cytology and histology (when available), Time of procedure, Proportion of successful imaging.
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