To compare effectiveness of platelet rich plasma (blood component) and tranexamic acid with dermaroller in melasma
- Conditions
- Health Condition 1: - Health Condition 2: L811- Chloasma
- Registration Number
- CTRI/2021/07/034631
- Lead Sponsor
- Department of Dermatology Government Medical College and Hospital Sector B Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 30
1.Patients with clinical diagnosis of melasma (bilaterally symmetrical distribution).
2.Patients above the age of 18 years and below the age of 50 years.
1.Patients with a history of bleeding disorders
2.Patients with hemoglobin level < 10 g/dl.
3.Patients with local inflammatory skin disorders at the site of the procedure.
4.Patients with use of systemic corticosteroids within 2 weeks or corticosteroid injection application within 1 month at the site of procedure.
5.Patient with known hypersensitivity to platelet rich plasma or any other form of blood components and to tranexamic acid.
6.Patients with any other facial dermatoses.
7.Patients on anticoagulants, oral contraceptive pills
8.Patients using photosensitizing an use of other depigmenting oral or topical agents.
9.Pregnancy and lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the comparative efficacy of platelet rich plasma therapy and tranexamic acid with microneedling in melasma.Timepoint: 0,3,6,9 weeks
- Secondary Outcome Measures
Name Time Method To assess adverse effects of platelet rich plasma and tranexamic acid with microneedling in melasma.Timepoint: 0,3,6,9 weeks